Evidence map›Paper›PMID 35360099›Full record

ArticleFrontiers in cellular and infection microbiology2022

Contribution of a Novel Pertussis Toxin-Like Factor in Mediating Persistent Otitis Media.

Longhuan Ma, Colleen Sedney, Yang Su, Kalyan K Dewan, Bodo Linz, Eric T Harvill

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Longhuan MaDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, United States.
Colleen SedneyDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, United States.
Yang SuDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, United States.
Kalyan K DewanDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, United States.
Bodo LinzDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, United States.
Eric T HarvillDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, United States.
University of Georgia · US

Funding

Evolution of the Bordetellae from Commensals to PathogensR01GM083113 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI HARVILL, ERIC T · 2008 to 2011
$2.1M
Are acellular vaccines driving the rise of pertactin-deficient Bordetella pertussisR21AI156293 · NIAID · UNIVERSITY OF GEORGIA · PI HARVILL, ERIC T · 2021 to 2022
$415k
Protection against Bordetella pertussis transmission conferred by established and novel vaccinesR21AI159347 · NIAID · UNIVERSITY OF GEORGIA · PI HARVILL, ERIC T · 2021 to 2022
$415k
Bacterial factors and host response in chronic otitis mediaR21DC018496 · NIDCD · UNIVERSITY OF GEORGIA · PI HARVILL, ERIC T · 2020 to 2021
$415k
An optimized mouse model of Bordetella pertussis infectionR21AI142678 · NIAID · UNIVERSITY OF GEORGIA · PI HARVILL, ERIC T · 2019 to 2020
$414k
Vaccine targeting catarrhal stage of pertussis diseaseR56AI149787 · NIAID · UNIVERSITY OF GEORGIA · PI HARVILL, ERIC T · 2020 to 2020
$369k
NIAID NIH HHS R21 AI142678NIAID NIH HHS R21 AI156293NIAID NIH HHS R21 AI159347NIAID NIH HHS R56 AI149787NIDCD NIH HHS R21 DC018496NIGMS NIH HHS R01 GM083113
6 · The paper itself

Abstract

Chronic otitis media (COM) is the long-term infection and inflammation of the middle ears typically caused by upper respiratory tract pathogens that are able to ascend the Eustachian tube. Our understanding of contributing factors is limited because human otopathogens cannot naturally colonize or persist in the middle ears of mice. We recently described a natural COM in mice caused by

Indexed as

Otitis MediaAnimalsBacteriaEar, MiddleInflammationMicePertussis ToxinPertussis ToxinBordetella pseudohinziichronic otitis media (COM)middle earPTx-like toxinT cell function

Identifiers

PMID35360099
PMCPMC8963424
OpenAlexW4221048869

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.