Evidence map›Paper›PMID 35361702›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

Synaptotagmins 1 and 7 Play Complementary Roles in Somatodendritic Dopamine Release.

Takuya Hikima, Paul Witkovsky, Latika Khatri, Moses V Chao, Margaret E Rice

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. The Synaptic Vesicle Priming Protein Munc13 Mediates Evoked Somatodendritic Dopamine Release.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  2. Article
  3. Article
  4. Kv4.2 Regulates Basal Synaptic Strength by Inhibiting R-Type Calcium Channels in the Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Article
  6. Article
  7. Synaptotagmin-1 is a CaCell reports · 2023
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Takuya HikimaDepartment of Neurosurgery, New York University Grossman School of Medicine, New York, New York 10016.
Paul WitkovskyDepartment of Neurosurgery, New York University Grossman School of Medicine, New York, New York 10016.
Latika KhatriDepartment of Cell Biology, New York University Grossman School of Medicine, New York, New York 10016.
Moses V ChaoDepartment of Cell Biology, New York University Grossman School of Medicine, New York, New York 10016.
Margaret E RiceDepartment of Neurosurgery, New York University Grossman School of Medicine, New York, New York 10016 margaret.rice@nyu.edu.ORCID https://orcid.org/0000-0003-1793-2798
New York University · US

Funding

U19 Supplement 2023-FroemkeU19NS107616 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RICHARD W TSIEN · 2018 to 2026
$36.4M
Diet, Insulin, Dopamine, and RewardR01DA050165 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CARR, KENNETH D, RICE, MARGARET E · 2020 to 2024
$3.0M
NIDA NIH HHS R01 DA050165NINDS NIH HHS U19 NS107616
6 · The paper itself

Abstract

The molecular mechanisms underlying somatodendritic dopamine (DA) release remain unresolved, despite the passing of decades since its discovery. Our previous work showed robust release of somatodendritic DA in submillimolar extracellular Ca

Indexed as

DopamineSubstantia NigraSynaptotagmin ISynaptotagminsAnimalsDendritesDopaminergic NeuronsElectric StimulationFemaleMaleMiceDopamineSynaptotagmin ISynaptotagminsSyt1 protein, mouseSyt7 protein, mouseautoreceptorsD2 dopamine receptorsexocytosisGIRK channelssubstantia nigrasynaptotagmin 1

Identifiers

PMID35361702
PMCPMC9097777
OpenAlexW4220822525

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.