ArticleThe Plant journal : for cell and molecular biology2022
Comparative analyses of American and Asian lotus genomes reveal insights into petal color, carpel thermogenesis and domestication.
Article in The Plant journal : for cell and molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 46 citations in OpenAlex.
- Two telomere-to-telomere Nelumbo genome assemblies reveal domestication history and empower precision breeding.Nature communications · 2026Article
- Genome-wide analysis of sunflower (Helianthus annuus) and Orobanche cumana reveals HaEXLA2 and HaEXLB2 as negative regulators of lignin-based resistance.Plant cell reports · 2026Article
- Lotus Seeds: Current Molecular Biology Insights and Future Perspectives as a Prominent Biological Resource.Plants (Basel, Switzerland) · 2026Review
- Genome-Wide Analysis ofPlants (Basel, Switzerland) · 2026Article
- Genome-wide identification ofFrontiers in plant science · 2026Article
- The chromosome-level genome of Hemerocallis middendorffii provides new insights into the floral scents and color biosynthesis in Chinese native daylily.BMC plant biology · 2025Article
- The Tissue Expression Divergence of the WUSCHEL-Related Homeobox Gene Family in the Evolution of Nelumbo.Plants (Basel, Switzerland) · 2025Article
- Genome-wide development of simple sequence repeat (SSR) markers at 2-Mb intervals in lotus (Nelumbo Adans.).BMC genomics · 2025Article
- Gene expression and metabolite levels converge in the thermogenic spadix of skunk cabbage.Plant physiology · 2024Article
- Evaluation and validation of suitable reference genes for quantitative real-time PCR analysis in lotus (Nelumbo nucifera Gaertn.).Scientific reports · 2024Article
- Technology-enabled great leap in deciphering plant genomes.Nature plants · 2024Review
- Transcription factor NnMYB5 controls petal color by regulating GLUTATHIONE S-TRANSFERASE2 in Nelumbo nucifera.Plant physiology · 2023Article
- Analysis of bZIP gene family in lotus (Nelumbo) and functional study of NnbZIP36 in regulating anthocyanin synthesis.BMC plant biology · 2023Article
- Expression inheritance and constraints on cis- and trans-regulatory mutations underlying lotus color variation.Plant physiology · 2023Article
- Metabolic profile and transcriptome reveal the mystery of petal blotch formation in rose.BMC plant biology · 2023Article
- Exploring domestication pattern in lotus: insights from dispensable genome assembly.Frontiers in plant science · 2023Article
- Genome-Wide Association Study for Screening and Identifying Potential Shin Color Loci in Ducks.Genes · 2022Article
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- Studies on Lotus Genomics and the Contribution to Its Breeding.International journal of molecular sciences · 2022Review
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Authors and funding
17 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nelumbo lutea (American lotus), which differs from Nelumbo nucifera (Asian lotus) morphologically, is one of the two remaining species in the basal eudicot family Nelumbonaceae. Here, we assembled the 843-Mb genome of American lotus into eight pseudochromosomes containing 31 382 protein-coding genes. Comparative analyses revealed conserved synteny without large chromosomal rearrangements between the genomes of American and Asian lotus and identified 29 533 structural variants (SVs). Carotenoid and anthocyanin pigments determine the yellow and red petal colors of American and Asian lotus, respectively. The structural genes encoding enzymes of the carotenoid and anthocyanin biosynthesis pathways were conserved between two species but differed in expression. We detected SVs caused by repetitive sequence expansion or contraction among the anthocyanin biosynthesis regulatory MYB genes. Further transient overexpression of candidate NnMYB5 induced anthocyanin accumulation in lotus petals. Alternative oxidase (AOX), uncoupling proteins (UCPs), and sugar metabolism and transportation contributed to carpel thermogenesis. Carpels produce heat with sugars transported from leaves as the main substrates, because there was weak tonoplast sugar transporter (TST) activity, and with SWEETs were highly expressed during thermogenesis. Cell proliferation-related activities were particularly enhanced in the warmer carpels compared with stamens during the cold night before blooming, which suggested that thermogenesis plays an important role in flower protogyny. Population genomic analyses revealed deep divergence between American and Asian lotus, and independent domestication affecting seed, rhizome, and flower traits. Our findings provide a high-quality reference genome of American lotus for exploring the genetic divergence and variation between two species and revealed possible genomic bases for petal color, carpel thermogenesis and domestication in lotus.
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