ArticleComputational toxicology (Amsterdam, Netherlands)2021
Abstract read
In one paragraph
Article in Computational toxicology (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Machine learning driven LDFrontiers in oncology · 2026Article
- Role of artificial intelligence in revolutionizing drug discovery.Fundamental research · 2025Review
- Mapping assays to the key characteristics of carcinogens to support decision-making.Database : the journal of biological databases and curation · 2025Article
- The key characteristics concept.Current opinion in toxicology · 2025Article
- IARC Workshop on the Key Characteristics of Carcinogens: Assessment of End Points for Evaluating Mechanistic Evidence of Carcinogenic Hazards.Environmental health perspectives · 2025Article
- New Theobromine Apoptotic Analogue with Anticancer Potential Targeting the EGFR Protein: Computational andACS omega · 2024Article
- ICH S1 prospective evaluation study and weight of evidence assessments: commentary from industry representatives.Frontiers in toxicology · 2024Article
- Developing a pragmatic consensus procedure supporting the ICH S1B(R1) weight of evidence carcinogenicity assessment.Frontiers in toxicology · 2024Article
- A new approach methodology to identify tumorigenic chemicals using short-term exposures and transcript profiling.Frontiers in toxicology · 2024Article
- Article
- Principles and Procedures for Assessment of Acute Toxicity IncorporatingComputational toxicology (Amsterdam, Netherlands) · 2022Article
- A new approach to the classification of carcinogenicity.Archives of toxicology · 2022Article
- Current status and future directions for a neurotoxicity hazard assessment framework that integratesComputational toxicology (Amsterdam, Netherlands) · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
41 authors.
Raymond R TiceRTice Consulting, Hillsborough, North Carolina, 27278, USA.
Arianna BassanInnovatune srl, 35129 Padova, Italy.
Alexander AmbergSanofi Preclinical Safety, Industriepark Höchst, 65926 Frankfurt, Germany.
Lennart T AngerGenentech, Inc., South San Francisco, California, 94080, USA.
Marc A BealHealthy Environments and Consumer Safety Branch, Health Canada, Government of Canada, Ottawa, Ontario, Canada K1A 0K9.
Phillip BellionDSM Nutritional Products Ltd., Kaiseraugst, Switzerland.
Romualdo BenigniAlpha-Pretox, Rome, Italy.
Jeffrey BirminghamGlaxoSmithKline, David Jack Centre for R&D, Ware, Hertfordshire, SG12 0DP, United Kingdom.
Alessandro BrigoRoche Pharmaceutical Research & Early Development, Pharmaceutical Sciences, Roche Innovation, Center Basel, F. Hoffmann-La Roche Ltd, CH-4070, Basel, Switzerland.
Frank BringezuMerck Healthcare KGaA, 64293 Darmstadt, Germany.
Lidia CerianiHumane Society International, 1000 Brussels, Belgium.
Ian CrooksBritish American Tobacco (Investments) Ltd, GR&D Centre, Southampton, SO15 8TL, United Kingdom.
Kevin CrossInstem, Columbus, Ohio, 43215, USA.
Rosalie ElespuruFood and Drug Administration, Center for Devices and Radiological Health, Silver Spring, Maryland, 20993, USA.
David M FaulknerChemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Marie C FortinDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey, 08855, USA.
Paul FowlerFSTox Consulting (Genetic Toxicology), Northamptonshire, United Kingdom.
Markus FrericksBASF SE, Limburgerhof, Germany.
Helga H J GeretsUCB BioPharma SRL, Braine-L'Alleud, Belgium.
Gloria D JahnkeDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, 27709, USA.
David R JonesClinical Trials Unit, MHRA, London E14 4PU.
Naomi L KruhlakFood and Drug Administration, Center for Drug Evaluation and Research, Silver Spring, Maryland, 20993, USA.
Elena Lo PiparoChemical Food Safety Group, Nestlé Research, CH-1000 Lausanne 26, Switzerland.
Juan Lopez-BelmonteCuts Ice Ltd Chemical Food Safety Group, Nestlé Research, CH-1000 Lausanne 26, Switzerland.
Amarjit LuniwalNorth American Science Associates (NAMSA) Inc., Minneapolis, Minnesota, 55426, USA.
Alice LuuHealthy Environments and Consumer Safety Branch, Health Canada, Government of Canada, Ottawa, Ontario, Canada K1A 0K9.
Federica MadiaEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Serena ManganelliChemical Food Safety Group, Nestlé Research, CH-1000 Lausanne 26, Switzerland.
Balasubramanian ManickamPfizer Inc, Groton, Connecticut, 06340, USA.
Jordi MestresIMIM Institut Hospital Del Mar d'Investigacions Mèdiques and Universitat Pompeu Fabra, Doctor Aiguader 88, Parc de Recerca Biomèdica, 08003 Barcelona, Spain; and Chemotargets SL, Baldiri Reixac 4, Parc Científic de Barcelona, 08028, Barcelona, Spain.
Amy L Mihalchik-BurhansGad Consulting Service, Raleigh, NC, 27609, USA.
Louise NeilsonBroughton Nicotine Services, Oak Tree House, Earby, Lancashire, BB18 6JZ United Kingdom.
Arun PandiriDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, 27709, USA.
Manuela PavanInnovatune srl, 35129 Padova, Italy.
Cynthia V RiderDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, 27709, USA.
John P RooneyIntegrated Laboratory Systems, LLC., Morrisville, North Carolina, 27560, USA.
Alejandra Trejo-MartinGilead Sciences Inc in Foster City, CA.
Karen H Watanabe-SailorSchool of Mathematical and Natural Sciences, Arizona State University, West Campus, Glendale, Arizona, 85306, USA.
Angela T WhiteGlaxoSmithKline, David Jack Centre for R&D, Ware, Hertfordshire, SG12 0DP, United Kingdom.
David WoolleyForthTox Limited, Linlithgow, United Kingdom.
Glenn J MyattInstem, Columbus, Ohio, 43215, USA.
Funding
Rapid response toxicology prediction platformR44ES026909 · NIEHS · LEADSCOPE, INC. · PI MYATT, GLENN JOHN · 2018 to 2019
$1000kNIEHS NIH HHS R44 ES026909
Abstract
Historically, identifying carcinogens has relied primarily on tumor studies in rodents, which require enormous resources in both money and time.
Indexed as
CancerCarcinogenesisComputational ToxicologyExpert AlertsHazard IdentificationIn SilicoKey Characteristics(Q)SARRead-acrossRisk Assessment
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.