Evidence map›Paper›PMID 35368552›Full record

ArticleCurrent addiction reports2021

Electronic Nicotine Delivery Systems (ENDS) Use and Pregnancy II: Perinatal Outcomes Following ENDS Use During Pregnancy.

Elise E DeVito, Tessa Fagle, Alicia M Allen, Raina D Pang, Nicole Petersen, Philip H Smith, Andrea H Weinberger

Abstract read
In one paragraph

Article in Current addiction reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Birth outcomes following intrauterine exposure to electronic nicotine delivery systems: a systematic review and meta-analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elise E DeVitoDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Tessa FagleDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Alicia M AllenDepartment of Family and Community Medicine, College of Medicine - Tucson, University of Arizona, Tucson, AZ, USA.
Raina D PangDepartment of Preventative Medicine, Keck School of Medicine of USC, and Department of Psychology, University of Southern California, Los Angeles, CA, USA.
Nicole PetersenDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, USA.
Philip H SmithDepartment of Kinesiology, Nutrition and Health, College of Education, Health and Society, Miami University, Oxford, OH, USA.
Andrea H WeinbergerFerkauf Graduate School of Psychology, Yeshiva University and Department of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.

Funding

Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and ChildrenR01HD100418 · NICHD · UNIVERSITY OF MINNESOTA · PI ALLEN, SHARON S · 2020 to 2025
$3.1M
Impact of Flavors on Nicotine Perception and Self-Administration via E-cigarettesR01DA046360 · NIDA · YALE UNIVERSITY · PI DEVITO, ELISE EVA · 2019 to 2021
$1.1M
Transcranial Magnetic Stimulation and Tobacco Use Disorder: A Network-Level Approach with Attention to Sex as a Biological VariableR00DA045749 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PETERSEN, NICOLE · 2021 to 2023
$902k
Ovarian Hormones Effect on Smoking BehaviorK01DA040043 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PANG, RAINA · 2015 to 2019
$875k
NICHD NIH HHS R01 HD100418NIDA NIH HHS K01 DA040043NIDA NIH HHS R00 DA045749NIDA NIH HHS R01 DA046360
6 · The paper itself

Abstract

Purpose of Review: This review examines the risk of adverse perinatal outcomes following electronic nicotine delivery system (ENDS) use during pregnancy, and considers whether there are sufficient data to support ENDS as a harm reduction approach during pregnancy. Recent Findings: Seven papers assessed perinatal outcomes following ENDS use during pregnancy. There was evidence that ENDS use was associated with increased risk for some adverse perinatal outcomes (e.g., small for gestational age). However, the repeated use of data sets, insufficient data (e.g., timing of ENDS use, type of ENDS products used), and limited samples size, contributed to mixed findings on the degree to which ENDS use (alone or in combination with combustible cigarettes (CC)) impacts the risk of adverse perinatal outcomes relative to CC smoking alone. Summary: The current data are still insufficient to support ENDS as a harm reduction approach, though findings do warrant concern and more detailed investigation of ENDS use during pregnancy. Future research directions, as well as implications for clinical recommendations and tobacco regulatory science are discussed.

Indexed as

e-cigaretteENDSperinatal outcomespregnancysmokingtobacco regulatory sciencevaping

Identifiers

PMID35368552
PMCPMC8974704

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.