Evidence map›Paper›PMID 35368914›Full record

Trial reportJournal of healthcare engineering2022

Efficacy of Human Adipose Derived Mesenchymal Stem Cells in Promoting Skin Wound Healing.

Lingcong Zhou, Hui Wang, Sidi Yao, Li Li, Xin Kuang

RetractedAbstract readRandomized Controlled TrialRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. The Utility of Fat Grafting to Manage Burn Scars: A Systematic Review.Journal of burn care & research : official publication of the American Burn Association · 2025
    Pooled it
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  11. Current and Future Developments in Wound Healing.Facial plastic surgery : FPS · 2023
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Lingcong ZhouDepartment of Plastic and Cosmetic Surgery, The Central Hospital of Yueyang, Yueyang, Hunan 414000, China.
Hui WangDepartment of Burn and Plastic Surgery, The First Affiliated Hospital of University of South China, Hengyang, Hunan 421000, China.
Sidi YaoHunan Industrial Technician College, Yueyang, Hunan 414000, China.
Li LiDepartment of Plastic and Cosmetic Surgery, The Central Hospital of Yueyang, Yueyang, Hunan 414000, China.
Xin KuangDepartment of Anesthesia,Affiliated Longhua People's Hospital, Southern Medical University, Longhua People's Hospital, Shenzhen 518000, China.ORCID 0000-0002-5565-0436

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this pilot clinical study is to evaluate the efficacy of human adipose derived mesenchymal stem cells (HAMSCs) treatment for the wound healing with patients. Methods: This study was a clinical trial to investigate the efficacy of human adipose derived mesenchymal stem cells treatment for the wound healing with patients. 346 patients with skin wounds attending the central hospital of Yue Yang were enrolled in the study, setting in the period from January 2016 to January 2021. Patients were randomly allocated into two groups: experimental group received treatment with human adipose derived mesenchymal stem cells for each 10 cm Results: No adverse events were recorded during the period of treatment. The granulation tissue coverage rate and thickness of granulation tissue after 10 days of treatment in experimental group were significantly improved compared with control group. Furthermore, the occurrence of bleeding of wound and suppurative wounds between two groups had significant difference ( Conclusion: The data in this pilot study indicated that human adipose derived mesenchymal stem cells may be a safe and effective alternative therapy for wound healing. Moreover, larger, placebo-controlled, perspective studies are necessity to evaluate the efficacy and safety of human adipose derived mesenchymal stem cells treatment for wound healing patients.

Indexed as

Adipose TissueMesenchymal Stem CellsHumansPilot ProjectsWound Healing

Identifiers

PMID35368914
PMCPMC8970852

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.