Evidence map›Paper›PMID 35369656›Full record

ArticleKidney3602021

Prevalence of Frailty in Patients Referred to the Kidney Transplant Waitlist.

George Worthen, Amanda Vinson, Héloise Cardinal, Steve Doucette, Nessa Gogan, Lakshman Gunaratnam, Tammy Keough-Ryan, Bryce A Kiberd, Bhanu Prasad, Kenneth Rockwood and 7 more

Abstract read
In one paragraph

Article in Kidney360, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

George WorthenDivision of Nephrology, Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0003-2437-0914
Amanda VinsonDivision of Nephrology, Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0002-9345-5252
Héloise CardinalDivision of Nephrology, Centre de Recherche du CHUM, Montreal, Quebec, Canada.
Steve DoucetteNova Scotia Health Authority, Halifax, Canada.
Nessa GoganDivision of Nephrology, Horizon Health Network, Saint John, New Brunswick, Canada.ORCID 0000-0003-2225-9374
Lakshman GunaratnamDivision of Nephrology, London Health Sciences Center, London, Ontario, Canada.ORCID 0000-0002-8845-1126
Tammy Keough-RyanDivision of Nephrology, Dalhousie University, Halifax, Nova Scotia, Canada.
Bryce A KiberdDivision of Nephrology, Dalhousie University, Halifax, Nova Scotia, Canada.
Bhanu PrasadDivision of Nephrology, Regina General Hospital, Regina, Saskatchewan, Canada.
Kenneth RockwoodDivision of Geriatric Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
Laura SillsNova Scotia Health Authority, Halifax, Canada.
Rita S SuriResearch Institute of the McGill University Health Center and Faculty of Medicine, McGill University, Montreal, Quebec, Canada.ORCID 0000-0002-0519-3927
Navdeep TangriChronic Disease Innovation Center, Winnipeg, Manitoba, Canada.ORCID 0000-0002-5075-6370
Michael WalshDivision of Nephrology, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0001-8292-2014
Kenneth WestDivision of Nephrology, Dalhousie University, Halifax, Nova Scotia, Canada.
Seychelle YohannaDivision of Nephrology, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0003-0404-7319
Karthik TennankoreDivision of Nephrology, Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0002-7919-6709

Funding

CIHR 407165
6 · The paper itself

Abstract

Background: Comparisons between frailty assessment tools for waitlist candidates are a recognized priority area for kidney transplantation. We compared the prevalence of frailty using three established tools in a cohort of waitlist candidates. Methods: Waitlist candidates were prospectively enrolled from 2016 to 2020 across five centers. Frailty was measured using the Frailty Phenotype (FP), a 37-variable frailty index (FI), and the Clinical Frailty Scale (CFS). The FI and CFS were dichotomized using established cutoffs. Agreement was compared using Results: Of 542 enrolled patients, 64% were male, 80% were White, and the mean age was 54±14 years. The prevalence of frailty by the FP was 16%. The mean FI score was 0.23±0.14, and the prevalence of frailty was 38% (score of ≥0.25). The median CFS score was three (IQR, 2-3), and the prevalence was 15% (score of ≥4). The Conclusion: Frailty prevalence varies by the measurement tool used, and agreement between these measurements is fair to moderate. This has implications for determining the optimal frailty screening tool for use in those being evaluated for kidney transplant.

Indexed as

FrailtyKidney TransplantationAgedFrail ElderlyGeriatric AssessmentHumansMalePrevalenceESRDfrailtygeriatric nephrologykidneykidney transplantationprevalencetransplantationwaiting lists

Identifiers

PMID35369656
PMCPMC8676383

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.