Evidence map›Paper›PMID 35370084›Full record

SynthesisWilderness & environmental medicine2022

Travel-Associated Venous Thromboembolism.

Isla McKerrow Johnson, Joseph Shatzel, Sven Olson, Tovah Kohl, Andrew Hamilton, Thomas G DeLoughery

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Wilderness & environmental medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Isla McKerrow JohnsonDepartment of Medicine, Mayo Clinic, Rochester, Minnesota.
Joseph ShatzelDivision of Hematology-Medical Oncology, Oregon Health & Science University, Portland, Oregon; Department of Biomedical Engineering, Oregon Health & Science University, Portland, Oregon.
Sven OlsonDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, Oregon.
Tovah KohlOregon Health & Science University Office of Clinical Integration and Evidence Based Practice, Portland, Oregon.
Andrew HamiltonOregon Health & Science University Office of Clinical Integration and Evidence Based Practice, Portland, Oregon.
Thomas G DeLougheryDivision of Hematology-Medical Oncology, Oregon Health & Science University, Portland, Oregon. Electronic address: delought@ohsu.edu.
Oregon Health & Science University · USMayo Clinic · USOregon Center for Clinical Investigation · US

Funding

Evaluating the Safety and Efficacy of Targeting the Contact Pathway to Prevent Device Associated Thrombosis.R01HL151367 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHATZEL, JOSEPH JAMES · 2020 to 2024
$1.5M
NHLBI NIH HHS R01 HL151367
6 · The paper itself

Abstract

introductionLong-distance travel is assumed to be a risk factor for venous thromboembolism (VTE). However, the available data have not clearly demonstrated the strength of this relationship, nor have they shown evidence for the role of thromboprophylaxis.

methodsWe performed a systematic review of the literature. We also summarized available guidelines from 5 groups.

resultsWe found 18 studies that addressed this question. Based on the data presented in the review, we conclude that there is an association between VTE and length of travel, but this association is mild to moderate in effect size with odds ratios between 1.1 and 4. A dose-response relationship between VTE and travel time was identified, with a 26% higher risk for every 2 h of air travel (P=0.005) starting after 4 h. The quality of evidence for both travel length and thromboprophylaxis was low. However, low-risk prophylactic measures such as graduated compression stockings were shown to be effective in VTE prevention. There is heterogeneity among the different practice guidelines. The guidelines generally concur that no prophylaxis is necessary in travelers without known thrombosis risk factors and advocate for conservative treatment such as compression stockings over pharmacologic prophylaxis.

conclusionsWe conclude air travel is a risk factor for VTE and that there is a dose relationship starting at 4 h. For patients with risk factors, graduated compression stockings are effective prophylaxis.

Indexed as

Venous ThromboembolismAnticoagulantsHumansRisk FactorsStockings, CompressionTravelAnticoagulantsairplaneembolismheparinstockingsthrombophlebitisthrombosis

Identifiers

PMID35370084
PMCPMC9149067
OpenAlexW4220824251

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.