Evidence map›Paper›PMID 35370884›Full record

SynthesisFrontiers in neurology2022

Identification of Risk Factors for Stroke in China: A Meta-Analysis of Prospective Cohort Studies.

Weizhuang Yuan, Bo Wu, Min Lou, Bo Song, Xiang Han, Feng Sheng, Weihai Xu

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Weizhuang YuanDepartment of Neurology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Bo WuDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Min LouDepartment of Neurology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China.
Bo SongDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xiang HanDepartment of Neurology, Huashan Hospital, Fudan University, Shanghai, China.
Feng ShengMedical Development, Amgen Biology Technology Consulting (Shanghai) Co., Ltd., Shanghai, China.
Weihai XuDepartment of Neurology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNFirst Affiliated Hospital of Zhengzhou University · CNHuashan Hospital · CNSecond Affiliated Hospital of Zhejiang University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to identify independent risk factors for first occurrence of stroke in Chinese individuals based on prospective cohort studies. Forty prospective cohort studies assessing 1,984,552 individuals were selected for the final meta-analysis. The identified risk factors for stroke in the Chinese population included old age (RR = 1.86, 95%CI: 1.47-2.36), hypertension (RR = 2.76, 95%CI: 2.26-3.37), cardiovascular disease history (RR = 1.98, 95%CI: 1.06-3.69), chronic kidney disease (RR = 1.65, 95%CI: 1.36-2.01), diabetes mellitus (RR = 1.71, 95%CI: 1.34-2.18), metabolic syndrome (RR = 1.59, 95%CI: 1.33-1.90), hyperglycemia (RR = 1.49, 95% CI: 1.31-1.69), obesity (RR = 1.45, 95%CI: 1.29-1.63), smoking (RR = 1.42, 95% CI: 1.27-1.58), prolonged sleep time (> 7.5 h, RR = 1.44, 95%CI: 1.19-1.75), higher levels of triglyceride (RR = 1.19, 95%CI: 1.07-1.32), C-reactive protein (RR = 1.34, 95%CI: 1.07-1.69). High fruit-rich diet (RR = 0.68, 95%CI: 0.58-0.80) was associated with a lower risk of stroke. The spectrum and power of risk factors varied among different cohort inclusion years. These findings provide a comprehensive tool for the primary prevention of stroke in Chinese individuals.

Indexed as

Chinesemeta–analysisprimary preventionrisk factorstroke

Identifiers

PMID35370884
PMCPMC8972128
OpenAlexW4220801070

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.