Evidence map›Paper›PMID 35371260›Full record

ReviewInternational journal of endocrinology2022

Effect of Intermittent Fasting Diet on Glucose and Lipid Metabolism and Insulin Resistance in Patients with Impaired Glucose and Lipid Metabolism: A Systematic Review and Meta-Analysis.

Xiaojie Yuan, Jiping Wang, Shuo Yang, Mei Gao, Lingxia Cao, Xumei Li, Dongxu Hong, Suyan Tian, Chenglin Sun

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 9 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 9 syntheses or guidelines pooled it, 88 citations in OpenAlex.

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  20. Intermittent fasting enhances cancer therapyWorld journal of clinical oncology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xiaojie YuanDepartment of Clinical Nutrition, First Hospital of Jilin University, 1 Xinmin Street, Changchun, 130021 Jilin, China.ORCID https://orcid.org/0000-0003-2690-422X
Jiping WangDepartment of Clinical Nutrition, First Hospital of Jilin University, 1 Xinmin Street, Changchun, 130021 Jilin, China.ORCID https://orcid.org/0000-0003-2489-1074
Shuo YangDepartment of Clinical Nutrition, First Hospital of Jilin University, 1 Xinmin Street, Changchun, 130021 Jilin, China.ORCID https://orcid.org/0000-0002-2579-8501
Mei GaoDepartment of Endocrinology and Metabolism, First Hospital of Jilin University, 1 Xinmin Street, Changchun, 130021 Jilin, China.ORCID https://orcid.org/0000-0003-2417-3056
Lingxia CaoDepartment of Endocrinology and Metabolism, First Hospital of Jilin University, 1 Xinmin Street, Changchun, 130021 Jilin, China.ORCID https://orcid.org/0000-0003-1688-2303
Xumei LiDepartment of Clinical Nutrition, First Hospital of Jilin University, 1 Xinmin Street, Changchun, 130021 Jilin, China.ORCID https://orcid.org/0000-0002-0706-6542
Dongxu HongDepartment of Clinical Nutrition, First Hospital of Jilin University, 1 Xinmin Street, Changchun, 130021 Jilin, China.ORCID https://orcid.org/0000-0002-0730-6403
Suyan TianDivision of Clinical Research, First Hospital of Jilin University, 1 Xinmin Street, Changchun, 130021 Jilin, China.ORCID https://orcid.org/0000-0002-5942-1542
Chenglin SunDepartment of Clinical Nutrition, First Hospital of Jilin University, 1 Xinmin Street, Changchun, 130021 Jilin, China.ORCID https://orcid.org/0000-0003-3570-1918
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The question of whether or not intermittent fasting diets improve the clinical indicators of glycolipid metabolism remains unclear. This study systematically reviewed the relevant clinical trials to evaluate the effects of intermittent fasting diet on glucose and lipid metabolism and insulin sensitivity in patients with metabolic syndrome. To evaluate the effect of intermittent fasting diet intervention on patients with disorders of glucose and lipid metabolism, random-effect or fixed-effect meta-analysis models were used to calculate the average difference before and after intermittent fasting diet intervention and the corresponding 95% confidence intervals (CIs). After intermittent fasting diet intervention, in terms of glucose metabolism, fasting blood glucose reduced by 0.15 mmol/L (95% CI: -0.23; -0.06), glycosylated hemoglobin reduced by 0.08 (95% CIs: -0.25; -0.10), insulin plasma levels reduced by 13.25 uUI (95% CIs: -16.69; -9.82), and HOMA-IR decreased by 0.31 on an average (95% CIs: -0.44; -0.19). In addition, BMI decreased by 0.8 kg/m

Identifiers

PMID35371260
PMCPMC8970877
OpenAlexW4220767201

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.