Evidence map›Paper›PMID 35372363›Full record

ArticleFrontiers in cell and developmental biology2022

Caspase-8 Deficient Osteoblastic Cells Display Alterations in Non-Apoptotic Pathways.

Barbora Vesela, Michael Killinger, Kamila Rihova, Petr Benes, Eva Svandová, Adela Kratochvilová, Filip Trcka, Karel Kleparnik, Eva Matalova

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Barbora VeselaInstitute of Animal Physiology and Genetics, Czech Academy of Sciences, Brno, Czechia.
Michael KillingerFaculty of Science, Masaryk University, Brno, Czechia.
Kamila RihovaFaculty of Science, Masaryk University, Brno, Czechia.
Petr BenesFaculty of Science, Masaryk University, Brno, Czechia.
Eva SvandováInstitute of Animal Physiology and Genetics, Czech Academy of Sciences, Brno, Czechia.
Adela KratochvilováInstitute of Animal Physiology and Genetics, Czech Academy of Sciences, Brno, Czechia.
Filip TrckaFaculty of Science, Masaryk University, Brno, Czechia.
Karel KleparnikInstitute of Analytical Chemistry, Czech Academy of Sciences, Brno, Czechia.
Eva MatalovaInstitute of Animal Physiology and Genetics, Czech Academy of Sciences, Brno, Czechia.
Masaryk University · CZCzech Academy of Sciences, Institute of Animal Physiology and Genetics · CZCzech Academy of Sciences, Institute of Analytical Chemistry · CZUniversity Hospital Brno · CZUniversity of Veterinary Sciences Brno · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caspase-8 is the key component of the receptor-mediated (extrinsic) apoptotic pathway. Immunological localization of active caspase-8 showed its presence in osteoblasts, including non-apoptotic ones. Further

Indexed as

apoptosisautophagyboneCRISPR/cas9MC3T3-E1osteogenesis

Identifiers

PMID35372363
PMCPMC8964645
OpenAlexW4220861488

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.