Evidence map›Paper›PMID 35378630›Full record

GuidelineArchives of osteoporosis2022

UK clinical guideline for the prevention and treatment of osteoporosis.

Celia L Gregson, David J Armstrong, Jean Bowden, Cyrus Cooper, John Edwards, Neil J L Gittoes, Nicholas Harvey, John Kanis, Sarah Leyland, Rebecca Low and 10 more

Erratum issuedOpen access · hybridAbstract readReviewPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Archives of osteoporosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 303 papers, 19 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
303citing papers in PubMed, 19 pooled it
92.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

303 citing papers in PubMed, 19 syntheses or guidelines pooled it, 551 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Pooled it
  6. Guideline
  7. Guideline
  8. Pooled it
  9. PTH1 receptor agonists for fracture risk: a systematic review and network meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Pooled it
  10. Guideline
  11. Pooled it
  12. Pooled it
  13. Pooled it
  14. Updated practice guideline for dual-energy X-ray absorptiometry (DXA).European journal of nuclear medicine and molecular imaging · 2025
    Guideline
  15. Pooled it
  16. Pooled it
  17. The Healing and therapeutic effects of perioperative bisphosphonate use in patients with fragility fractures: meta-analysis of 19 clinical trials.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Pooled it
  18. Guideline
  19. Pooled it
  20. Trial

243 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 17 institutions in 2 countries.

Celia L GregsonMusculoskeletal Research Unit, Bristol Medical School, Learning and Research Building, University of Bristol, Southmead Hospital, Bristol, BS10 5NB, UK. celia.gregson@bristol.ac.uk.
David J ArmstrongWestern Health and Social Care Trust (NI), Nutrition Innovation Centre for Food and Health, Ulster University, and Visiting Professor, Belfast, Northern Ireland.
Jean BowdenMusculoskeletal Research Unit, Bristol Medical School, Learning and Research Building, University of Bristol, Southmead Hospital, Bristol, BS10 5NB, UK.
Cyrus CooperMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
John EdwardsPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, Staffordshire, and Wolstanton Medical Centre, Newcastle under Lyme, UK.
Neil J L GittoesCentre for Endocrinology, Diabetes and Metabolism, Queen Elizabeth Hospital, University Hospitals Birmingham & University of Birmingham, Birmingham, UK.
Nicholas HarveyMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
John KanisMary McKillop Institute for Health Research, Australian Catholic University, Melbourne, Australia and Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK.
Sarah LeylandRoyal Osteoporosis Society, Bath, UK.
Rebecca LowAbingdon and Specialty Doctor in Metabolic Bone Disease, Marcham Road Health Centre, Nuffield Orthopaedic Centre, Oxford, UK.
Eugene McCloskeyDepartment of Oncology & Metabolism, MRC Versus Arthritis Centre for Integrated Research in Musculoskeletal Ageing (CIMA), Mellanby Centre for Musculoskeletal Research, University of Sheffield, Sheffield, UK.
Katie MossSt George's University Hospital, London, UK.
Jane ParkerMusculoskeletal Research Unit, Bristol Medical School, Learning and Research Building, University of Bristol, Southmead Hospital, Bristol, BS10 5NB, UK.
Zoe PaskinsSchool of Medicine, Keele University, Keele, Haywood Academic Rheumatology Centre, Haywood Hospital, Midlands Partnership NHS Foundation Trust, Stoke-on-Trent, UK.
Kenneth PooleDepartment of Medicine, University of Cambridge, Cambridge, UK.
David M ReidUniversity of Aberdeen, Aberdeen, Scotland.
Mike StoneUniversity Hospital Llandough, Cardiff and Vale University Health Board, Llandough, UK.
Julia ThomsonRoyal Osteoporosis Society, Bath, UK.
Nic VineMusculoskeletal Research Unit, Bristol Medical School, Learning and Research Building, University of Bristol, Southmead Hospital, Bristol, BS10 5NB, UK.
Juliet CompstonUniversity of Cambridge, School of Clinical Medicine, Cambridge, UK.
Royal Osteoporosis Society · GBSouthmead Hospital · GBUniversity of Bristol · GBAustralian Catholic University · AUCardiff and Vale University Health Board · GBKeele University · GBMRC Lifecourse Epidemiology Unit · GBNIHR Cambridge Biomedical Research CentreNuffield Orthopaedic Centre · GBOxford BioMedica (United Kingdom) · GBSt George's Hospital · GBUniversity of Aberdeen · GBUniversity of Birmingham · GBUniversity of Cambridge · GBUniversity of Sheffield · GBUniversity of Ulster · GBVersus Arthritis · GB

Funding

Department of Health CS-2018-18-ST2-010Medical Research Council G0400491Medical Research Council MC_PC_21000Medical Research Council MC_PC_21001Medical Research Council MC_PC_21003Medical Research Council MC_PC_21022Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/1Medical Research Council MR/P020941/1
6 · The paper itself

Abstract

The National Osteoporosis Guideline Group (NOGG) has revised the UK guideline for the assessment and management of osteoporosis and the prevention of fragility fractures in postmenopausal women, and men age 50 years and older. Accredited by NICE, this guideline is relevant for all healthcare professionals involved in osteoporosis management.

introductionThe UK National Osteoporosis Guideline Group (NOGG) first produced a guideline on the prevention and treatment of osteoporosis in 2008, with updates in 2013 and 2017. This paper presents a major update of the guideline, the scope of which is to review the assessment and management of osteoporosis and the prevention of fragility fractures in postmenopausal women, and men age 50 years and older.

methodsWhere available, systematic reviews, meta-analyses and randomised controlled trials were used to provide the evidence base. Conclusions and recommendations were systematically graded according to the strength of the available evidence.

resultsReview of the evidence and recommendations are provided for the diagnosis of osteoporosis, fracture-risk assessment and intervention thresholds, management of vertebral fractures, non-pharmacological and pharmacological treatments, including duration and monitoring of anti-resorptive therapy, glucocorticoid-induced osteoporosis, and models of care for fracture prevention. Recommendations are made for training; service leads and commissioners of healthcare; and for review criteria for audit and quality improvement.

conclusionThe guideline, which has received accreditation from the National Institute of Health and Care Excellence (NICE), provides a comprehensive overview of the assessment and management of osteoporosis for all healthcare professionals involved in its management. This position paper has been endorsed by the International Osteoporosis Foundation and by the European Society for the Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases.

Indexed as

Fractures, BoneOsteoporosisBone DensityFemaleHumansMaleMiddle AgedRisk AssessmentUnited KingdomFractureGuidelineNOGGOsteoporosis

Identifiers

PMID35378630
PMCPMC8979902
OpenAlexW4226048997

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.