Evidence map›Paper›PMID 35387839›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2022

Pharmacologically Inferred Glycolysis and Glutaminolysis Requirement of B Cells in Lupus-Prone Mice.

Seung-Chul Choi, Wei Li, Xiaojuan Zhang, Nathalie Kanda, Leilani Zeumer-Spataro, Xiangyu Teng, Laurence Morel

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 21 citations in OpenAlex.

  1. A guide to B cell metabolism.Nature reviews. Immunology · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Immunometabolism in systemic lupus erythematosus.Nature reviews. Rheumatology · 2025
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Glutaminolysis is a Potential Therapeutic Target for Kidney Diseases.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  15. Article
  16. Article
  17. Glucose Requirement of Antigen-Specific Autoreactive B Cells and CD4+ T Cells.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Seung-Chul ChoiDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL.ORCID 0000-0001-6230-9087
Wei LiDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL.ORCID 0000-0001-9835-8470
Xiaojuan ZhangDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL.
Nathalie KandaDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL.ORCID 0000-0002-1087-652X
Leilani Zeumer-SpataroDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL.
Xiangyu TengDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL.
Laurence MorelDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL morel@ufl.edu.
University of Florida · US

Funding

Determinants of follicular helper T cell expansion in lupusR01AI154630 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MOREL, LAURENCE, ZADEH, MANSOUR M · 2020 to 2025
$6.3M
Bacterial surface layer-specific immune protection against gut microbial infectionR01DK109560 · NIDDK · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ZADEH, MANSOUR M · 2016 to 2024
$3.5M
Targeting follicular helper CD4 T cells in SLER37AI128901 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Laurence Morel · 2022 to 2026
$2.3M
Targeting follicular helper CD4 T cells in SLER01AI128901 · NIAID · UNIVERSITY OF FLORIDA · PI MOREL, LAURENCE · 2017 to 2021
$1.8M
NIAID NIH HHS R01 AI128901NIAID NIH HHS R01 AI154630NIAID NIH HHS R37 AI128901NIDDK NIH HHS R01 DK109560
6 · The paper itself

Abstract

Several studies have shown an enhanced metabolism in the CD4

Indexed as

B-LymphocytesDiazooxonorleucineAnimalsGlycolysisHumansMiceMice, CongenicMice, Inbred C57BLT-Lymphocytes, Helper-InducerDiazooxonorleucine

Identifiers

PMID35387839
PMCPMC9050845
OpenAlexW4224938586

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.