Evidence map›Paper›PMID 35388742›Full record

ArticleThe Libyan journal of medicine2022

Reversibility of pancreatic β-cells dysfunction after vitamin D and calcium supplementation: a pilot study in a population of obese and prepubescent North-African children.

Meriem Gaddas, Imed Latiri, Raoudha Kebaili, Ilhem Kacem, Nesrine Jaballah, Jihene Maatoug, Mohamed Salaani, Lamia Boughammoura, Helmi Ben Saad

Open access · goldAbstract read
In one paragraph

Article in The Libyan journal of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Meriem GaddasFaculté de Médecine de Sousse, Service de Physiologie et Explorations Fonctionnelles, Université de Sousse, Sousse, Tunisie.ORCID 0000-0002-8836-767X
Imed LatiriFaculté de Médecine de Sousse, Service de Physiologie et Explorations Fonctionnelles, Université de Sousse, Sousse, Tunisie.ORCID 0000-0002-6074-4736
Raoudha KebailiPaediatrics Department, Farhat HACHED Hospital of Sousse, University of Sousse, Sousse, Tunisia.ORCID 0000-0003-3150-5549
Ilhem KacemBasic Health Center «Sousse Jawhara", Outpatient consultation, Sousse, Tunisia.ORCID 0000-0001-5713-8594
Nesrine JaballahPaediatrics Department, Farhat HACHED Hospital of Sousse, University of Sousse, Sousse, Tunisia.ORCID 0000-0003-1144-7054
Jihene MaatougEpidemiology Department, Farhat HACHED Hospital of Sousse, University of Sousse, Sousse, Tunisia.ORCID 0000-0001-8857-2238
Mohamed SalaaniPaediatrics Department, Farhat HACHED Hospital of Sousse, University of Sousse, Sousse, Tunisia.
Lamia BoughammouraPaediatrics Department, Farhat HACHED Hospital of Sousse, University of Sousse, Sousse, Tunisia.
Helmi Ben SaadFaculté de Médecine de Sousse, Service de Physiologie et Explorations Fonctionnelles, Université de Sousse, Sousse, Tunisie.ORCID 0000-0002-7477-2965
University of Sousse · TNHôpital Farhat Hached · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanisms of diabetogenesis in children remain largely obscure. This study aimed to determine the impact of vitamin D and calcium supplementation on pancreatic β-cells function in terms of insulin secretion and sensitivity. This was a quasi-experimental study involving 30 obese and prepubescent Tunisian children (57% boys). During three months, the children received calcium and vitamin D supplementation at therapeutic doses. An oral glucose tolerance test (OGTT) was performed at the beginning and at the end of the study. The following metabolic definitions were applied:

Indexed as

CalciumInsulin ResistanceBlood GlucoseChildDietary SupplementsFemaleHumansInsulinMaleObesityPilot ProjectsVitamin DVitaminsBlood GlucoseCalciumInsulinVitamin DVitaminsDiabetes-mellitusinsulin productionobesityPaediatricsTunisia

Identifiers

PMID35388742
PMCPMC9004520
OpenAlexW4223573812

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.