Evidence map›Paper›PMID 35402240›Full record

ArticleFrontiers in oncology2022

Re-Expression of ERα and AR in Receptor Negative Endocrine Cancers

Vikas Sharma, Jayadev Joshi, I-Ju Yeh, YongQiu Doughman, Daniel Blankenberg, David Wald, Monica M Montano

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. [Neutrophil-derived Microvesicles Regulate DNA Methylation of theSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Article
  2. Article
  3. Epigenetic Modulation of Estrogen Receptor Signaling in Ovarian Cancer.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Vikas SharmaDepartment of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Jayadev JoshiGenomic Medicine Institute, Cleveland Clinic Lerner Research Institute, Cleveland, OH, United States.
I-Ju YehDepartment of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
YongQiu DoughmanDepartment of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Daniel BlankenbergGenomic Medicine Institute, Cleveland Clinic Lerner Research Institute, Cleveland, OH, United States.
David WaldDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Monica M MontanoDepartment of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
University School · USCleveland Clinic Lerner College of Medicine · USCase Western Reserve University · US

Funding

HEXIM1 regulation of transcriptional networks critical for tumor suppressionR01CA195558 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI MONTANO, MONICA · 2016 to 2020
$1.8M
NCI NIH HHS R01 CA195558
6 · The paper itself

Abstract

DNA methylation, catalyzed by DNA methyltransferase (DNMT), is a well-characterized epigenetic modification in cancer cells. In particular, promoter hypermethylation of

Indexed as

androgen receptorbreast cancerDnmt1estrogen receptorGSK3prostate cancer

Identifiers

PMID35402240
PMCPMC8988137
OpenAlexW4221104261

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.