Evidence map›Paper›PMID 35403089›Full record

ArticlePhytomedicine plus : international journal of phytotherapy and phytopharmacology2022

Research on the mechanism of berberine in the treatment of COVID-19 pneumonia pulmonary fibrosis using network pharmacology and molecular docking.

Junfeng Cao, Lianglei Li, Li Xiong, Chaochao Wang, Yijun Chen, Xiao Zhang

Open access · goldAbstract read
In one paragraph

Article in Phytomedicine plus : international journal of phytotherapy and phytopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Molecular mechanism of Dang-Shen-Yu-Xing decoction againstFrontiers in veterinary science · 2024
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Antibacterial activity of a berberine nanoformulation.Beilstein journal of nanotechnology · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Junfeng CaoClinical Laboratory Medicine, Chengdu Medical College, Chengdu, China.
Lianglei LiCenter for Experimental Technology of Preclinical Medicine, Chengdu Medical College, No.783 Xindu Road, Xindu District, Chengdu, Sichuan 610500, China.
Li XiongClinical Laboratory Medicine, Chengdu Medical College, Chengdu, China.
Chaochao WangClinical Laboratory Medicine, Chengdu Medical College, Chengdu, China.
Yijun ChenClinical Laboratory Medicine, Chengdu Medical College, Chengdu, China.
Xiao ZhangCenter for Experimental Technology of Preclinical Medicine, Chengdu Medical College, No.783 Xindu Road, Xindu District, Chengdu, Sichuan 610500, China.
Chengdu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ARDS, acute respiratory distress syndromeBerberineBP, biological processCC, cellular componentCCL2, chemokine ligand2COVID-19COVID-19, corona virus disease 2019COVID-19 pneumoniaECM, extracellular matrixEMT, epithelial-mesenchymal cell transformationFOXM1, forkhead box M1Fsp1, fibroblast-specific protein 1GO, gene ontologyHIF-1, hypoxia inducible factorIBD, inflammatory bowel diseaseIL-12, interleukin 12IL-6, interleukin 6JAK, Janus kinaseKEGG, Kyoto encyclopedia of genes and genomesLR-MSCs, mesenchymal stem cellsMF, molecular functionMMP14, matrix metalloproteinase 14MMP7, matrix metalloproteinase 7Molecular dockingNetwork pharmacologyNF-κB, nuclear transcription factorNOS, nitric oxide synthaseOTUB1, deubiquitinasePAI-1, plasminogen activator inhibitor 1PPI, protein-protein interactionPulmonary fibrosissIL-6R, interleukin 6 receptorSTAT3, transcription activatorTGF-β, transforming growth factor-βTNF-α, tumor necrosis factor-αα-SMA, α-smooth muscle actin

Identifiers

PMID35403089
PMCPMC8895682
OpenAlexW4214861073

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.