ArticleClinical cardiology2022
The association between systemic inflammatory response index and in-hospital mortality in patients with infective endocarditis.
Article in Clinical cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 14 citations in OpenAlex.
- Article
- Neurological complications as a predictor of in-hospital mortality in infective endocarditis: 11 years' experience of tertiary center.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Association Between the Systemic Inflammatory Response Index and Severe Infection in Patients with Diabetic Foot.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Systemic Inflammatory Response Index Has a Value for the Early Diagnosis and Short-Term Prognostic Assessment of Severe Pneumonia in the Elderly.Canadian respiratory journal · 2026Article
- Hematological Parameter-Derived Inflammatory Scores in Non-Pancreatic Hyperlipasemia (NPHL)-The Prognosis Lies in the Blood.Biomedicines · 2025Article
- Prognostic significance of systemic inflammation response index, systemic immune-inflammation index and neutrophil-to-lymphocyte ratio in patients with chronic subdural hematoma after burr hole drainage.Frontiers in neurology · 2025Article
- Article
- Determining Diagnostic Sensitivity: A Comparison of Rose Bengal Test, Coombs Gel Test, ELISA and Bacterial Culture in Brucellosis Diagnosis-Analyzing Clinical Effectiveness in Light of Inflammatory Markers.Diagnostics (Basel, Switzerland) · 2024Article
- Systemic inflammation response index as a prognostic factor for patients with sepsis-associated acute kidney injury: a retrospective observational study.The Journal of international medical research · 2024Observational
- The association between systemic inflammatory response index and in-hospital mortality in patients with infective endocarditis.Clinical cardiology · 2022Article
- The Prognostic Value of Hematologic Inflammatory Markers in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
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5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundInfective endocarditis (IE) has a significant mortality, and early identification of high-risk patients and prediction of poor outcomes is of great significance. In recent years, increasing research has revealed the predictors associated with infective endocarditis prognosis. Systemic inflammatory response index (SIRI) is an important new indicator of inflammation. So far, there have been no reports on the relationship between SIRI and the prognosis of IE patients. HYPOTHESIS: The purpose of this study was to explore the value of SIRI in predicting in-hospital death for patients with infective endocarditis (IE), so as to provide reference for improving the prognosis of patients with IE.
methodA retrospective analysis was performed on the clinical data of patients with IE admitted to the First Affiliated Hospital of Nanjing Medical University from January 2017 to December 2019. SIRI was calculated according to the blood routine results of patients at admission; receiver operating characteristic curve was employed to determined the optimal cutoff value of SIRI. Patients were divided into groups (low SIRI group and high SIRI group; nonsurvivor group and survivor group) according to the levels of SIRI or their prognosis, and the general clinical features of the two groups were compared. Univariate and multivariate logistic regression analysis were performed to analyze the independent prognostic factors of in-hospital death in IE patients.
resultsA total of 147 IE patients meeting the diagnostic criteria were included, including 102 males (69.4%) and 45 females (30.6%). There was statistically significant difference in SIRI level between nonsurvivor group and survivor group (p < .05). After adjusting for the related factors, the risk of in-hospital death in the high SIRI was still a risk of in-hospital death with statistical significance (hazard ratio = 5.053, 95% confidence interval: 1.426-17.905, p = .012).
conclusionsHigher SIRI level is independently associated with the risk of in-hospital death in IE patients, and can be an independent predictor of poor outcome in IE patients.
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