Evidence map›Paper›PMID 35406421›Full record

ReviewCancers2022

Anaplastic Large Cell Lymphoma: Molecular Pathogenesis and Treatment.

Xin-Rui Zhang, Pham-Ngoc Chien, Sun-Young Nam, Chan-Yeong Heo

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
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  9. Review
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  15. Review
  16. PAX Family, Master Regulator in Cancer.Diagnostics (Basel, Switzerland) · 2025
    Review
  17. Review
  18. Review
  19. Article
  20. Silicone breast implant-associated pathologies and T cell-mediated responses.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Xin-Rui ZhangDepartment of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, Seoul 03080, Korea.ORCID 0000-0002-5615-6341
Pham-Ngoc ChienDepartment of Plastic & Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam 13620, Korea.ORCID 0000-0003-1419-3766
Sun-Young NamDepartment of Plastic & Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam 13620, Korea.
Chan-Yeong HeoDepartment of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, Seoul 03080, Korea.ORCID 0000-0001-9003-7365
Seoul National University · KRSeoul National University Bundang Hospital · KR

Funding

Institute of Information & Communications Technology Planning & Evaluation (IITP) grant funded by the Korea government (MSIT) No. 2020-0-00990
6 · The paper itself

Abstract

Anaplastic large cell lymphoma (ALCL) is an uncommon type of non-Hodgkin's lymphoma (NHL), as well as one of the subtypes of T cell lymphoma, accounting for 1 to 3% of non-Hodgkin's lymphomas and around 15% of T cell lymphomas. In 2016, the World Health Organization (WHO) classified anaplastic large cell lymphoma into four categories: ALK-positive ALCL (ALK+ALCL), ALK-negative ALCL (ALK-ALCL), primary cutaneous ALCL (pcALCL), and breast-implant-associated ALCL (BIA-ALCL), respectively. Clinical symptoms, gene changes, prognoses, and therapy differ among the four types. Large lymphoid cells with copious cytoplasm and pleomorphic characteristics with horseshoe-shaped or reniform nuclei, for example, are found in both ALK+ and ALK-ALCL. However, their epidemiology and pathogenetic origins are distinct. BIA-ALCL is currently recognized as a new provisional entity, which is a noninvasive disease with favorable results. In this review, we focus on molecular pathogenesis and management of anaplastic large cell lymphoma.

Indexed as

ALK (anaplastic lymphoma kinase)anaplastic large cell lymphoma (ALCL)breast-implant-associated ALCLmanagementpathogenesis

Identifiers

PMID35406421
PMCPMC8997054
OpenAlexW4220990553

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.