Evidence map›Paper›PMID 35412290›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Live Imaging of Axonal Transport in the Adult Drosophila Central Nervous System.

Wayne Robinson, Tanja A Godenschwege

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Wayne RobinsonDepartment of Biological Sciences, Florida Atlantic University, Jupiter, FL, USA.
Tanja A GodenschwegeDepartment of Biological Sciences, Florida Atlantic University, Jupiter, FL, USA. godensch@fau.edu.
Florida Atlantic University · US

Funding

Nuclear function of L1-type CAMs in the drosophila nervous systemR15NS090043 · NINDS · FLORIDA ATLANTIC UNIVERSITY · PI GODENSCHWEGE, TANJA ANGELA · 2015 to 2015
$448k
NINDS NIH HHS R15 NS090043
6 · The paper itself

Abstract

Live imaging of axons allows for the determination of motility and directionality of proteins or organelles. In Drosophila, axonal transport has been predominantly characterized in peripheral neurons, such as larval motor neurons and sensory neurons of the adult wing. As peripheral neurons and central nervous system (CNS) neurons are inherently different, we provide a method to live-image axonal transport of CNS neurons in the cervical connective using an upright or inverted microscope. The method involves dissecting and mounting an entire CNS in a glass bottom petri dish, which is suitable for imaging of nearly any axon in cervical connective. Here, we show an example for simultaneous imaging of both giant fiber axons, which are part of the fly's escape response circuitry, and due to their large diameter provide outstanding resolution.

Indexed as

Axonal TransportDrosophilaAnimalsAxonsCentral Nervous SystemSensory Receptor CellsAxon transportCentral nervous systemDrosophilaGiant fiberLive imagingOrganelle traffickingWhole-mount dissection

Identifiers

PMID35412290
OpenAlexW4226039691

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.