Evidence map›Paper›PMID 35418993›Full record

ArticleFrontiers in immunology2022

Gill and Liver Transcript Expression Changes Associated With Gill Damage in Atlantic Salmon (

Mohamed Emam, Albert Caballero-Solares, Xi Xue, Navaneethaiyer Umasuthan, Barry Milligan, Richard G Taylor, Rachel Balder, Matthew L Rise

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Dynamics of Gill Responses to a Natural Infection withAnimals : an open access journal from MDPI · 2024
    Article
  4. Article
  5. Article
  6. Transcriptional Responses of Stress-Related Genes in Pale Chub (International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Mohamed EmamDepartment of Ocean Sciences, Memorial University of Newfoundland, St. John's, NL, Canada.
Albert Caballero-SolaresDepartment of Ocean Sciences, Memorial University of Newfoundland, St. John's, NL, Canada.
Xi XueDepartment of Ocean Sciences, Memorial University of Newfoundland, St. John's, NL, Canada.
Navaneethaiyer UmasuthanDepartment of Ocean Sciences, Memorial University of Newfoundland, St. John's, NL, Canada.
Barry MilliganCermaq Canada, Campbell River, BC, Canada.
Richard G TaylorCargill Animal Nutrition and Health, Elk River, MN, United States.
Rachel BalderCargill Animal Nutrition and Health, Elk River, MN, United States.
Matthew L RiseDepartment of Ocean Sciences, Memorial University of Newfoundland, St. John's, NL, Canada.
Memorial University of Newfoundland · CACargill (United States) · USCermaq (Canada) · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gill damage represents a significant challenge in the teleost fish aquaculture industry globally, due to the gill's involvement in several vital functions and direct contact with the surrounding environment. To examine the local and systemic effects accompanying gill damage (which is likely to negatively affect gill function) of Atlantic salmon, we performed a field sampling to collect gill and liver tissue after several environmental insults (e.g., harmful algal blooms). Before sampling, gills were visually inspected and gill damage was scored; gill scores were assigned from pristine [gill score 0 (GS0)] to severely damaged gills (GS3). Using a 44K salmonid microarray platform, we aimed to compare the transcriptomes of pristine and moderately damaged (i.e., GS2) gill tissue. Rank Products analysis (5% percentage of false-positives) identified 254 and 34 upregulated and downregulated probes, respectively, in GS2 compared with GS0. Differentially expressed probes represented genes associated with functions including gill remodeling, wound healing, and stress and immune responses. We performed gill and liver qPCR for all four gill damage scores using microarray-identified and other damage-associated biomarker genes. Transcripts related to wound healing (e.g.,

Indexed as

GillsSalmo salarAnimalsBiomarkersLiverPPAR gammaBiomarkersPPAR gammaenvironmental stressorsimmune responsemoderate gill damagetranscriptomic responsewound healing

Identifiers

PMID35418993
PMCPMC8996064
OpenAlexW4221131497

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.