Evidence map›Paper›PMID 35429733›Full record

ReviewCell calcium2022

VDAC2 as a novel target for heart failure: Ca

Paul Rosenberg

Open access · greenAbstract readReview
In one paragraph

Review in Cell calcium, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Paul RosenbergDepartment of Medicine, Duke University School of Medicine, Durham, NC 27705, United States. Electronic address: paul.rosenberg@duke.edu.
Duke University · US

Funding

REHAB-HF: A Trial of Rehabilitation Therapy in Older Acute Heart Failure PatientsR01AG045551 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KITZMAN, DALANE W · 2014 to 2018
$6.8M
STIM1 and metabolic flexibilityR01DK109911 · NIDDK · DUKE UNIVERSITY · PI ROSENBERG, PAUL B · 2017 to 2021
$2.9M
NIA NIH HHS R01 AG045551NIDDK NIH HHS R01 DK109911
6 · The paper itself

Abstract

Despite a growing number of successful therapies, heart failure remains the most common cause of death and disability worldwide. Thus, new and novel therapeutic strategies are urgently needed. Mitochondria of cardiomyocytes generate ATP that is needed to power cardiac contraction. Mitochondrial-derived ATP activate myosin ATPase at the sarcomere and the sarcoplasmic reticular (SR) ATPase Ca

Indexed as

Heart FailureSarcoplasmic ReticulumAdenosine TriphosphateCalciumHumansMitochondriaMitochondria, HeartMyocytes, CardiacSarcomeresVoltage-Dependent Anion Channel 2Adenosine TriphosphateCalciumVDAC2 protein, humanVoltage-Dependent Anion Channel 2CalciumContractilityExcitation contraction couplingHeart failureMitochondriaMitochondrial Ca(2+) uptake transporterVoltage dependent anion channels

Identifiers

PMID35429733
PMCPMC9459362
OpenAlexW4220756385

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.