Evidence map›Paper›PMID 35431576›Full record

ArticleInternational journal of general medicine2022

The Association of Axial Length with Macular Microvascular Changes in Chinese Diabetic Retinopathy Patients.

Qian Zhang, Liu Yang, Xiaoling Xu, Xinmei Lan, Ziwei Wang, Yali Sun, Shuhua Fu, Yu Xiong

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Qian ZhangDepartment of Ophthalmology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, People's Republic of China.
Liu YangDepartment of Ophthalmology, The First People's Hospital of Fuzhou City, Fuzhou, 344000, People's Republic of China.
Xiaoling XuDepartment of Ophthalmology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, People's Republic of China.
Xinmei LanDepartment of Ophthalmology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, People's Republic of China.
Ziwei WangDepartment of Ophthalmology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, People's Republic of China.
Yali SunDepartment of Ophthalmology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, People's Republic of China.
Shuhua FuDepartment of Ophthalmology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, People's Republic of China.
Yu XiongDepartment of Ophthalmology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, People's Republic of China.
Nanchang University · CNFujian Provincial People's Hospital · CNSecond Affiliated Hospital of Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To use optical coherence tomography angiography (OCTA) to compare macular blood flow density, subfoveal choroidal thickness (SFCT) and outer retina thickness (ORT) in non-proliferative diabetic retinopathy (NPDR) patients with different axial length (AL). Methods: Total 42 patients with NPDR with different eye axis were divided into three groups: group A: 22 mm≤AL<24 mm; group B: 24 mm≤AL<26 mm; group C: AL≥26 mm. Superficial capillary plexus (SCP) in the macular area, vascular length density (VLD) and vascular perfusion density (VPD) in the foveal region, the parafoveal region, the perifoveal region and whole macular region were analyzed. The correlations among axial length, macular microvascular density, SFCT and outer retinal thickness (ORT) were analyzed. Results: Compared with group A and B, VLD and VPD in group C were significantly lower except the foveal region, and VLD and VPD were negatively correlated with AL. The difference in SFCT among group A, B and C was significant, and SFCT was negatively correlated with AL. Compared with group A, parafoveal ORT in group C was significantly lower than that in group A, and parafoveal ORT was negatively correlated with AL. Conclusion: In NPDR patients with different AL, macular microvascular density, SFCT, and parafoveal ORT decreased with the increase of AL.

Indexed as

axial lengthchoroidal thicknessdiabetic retinopathyoptical coherence tomography angiographyretinal vascular density

Identifiers

PMID35431576
PMCPMC9005356
OpenAlexW4225434587

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.