Evidence map›Paper›PMID 35431989›Full record

ReviewFrontiers in physiology2022

Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Pregnancy. A Non-systematic Review of Clinical Presentation, Potential Effects of Physiological Adaptations in Pregnancy, and Placental Vascular Alterations.

Paola Ayala-Ramírez, Marcelo González, Carlos Escudero, Laura Quintero-Arciniegas, Fernanda R Giachini, Raiany Alves de Freitas, Alicia E Damiano, Reggie García-Robles

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Coronavirus Disease-2019 in Pregnancy.Clinics in chest medicine · 2023
    Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Paola Ayala-RamírezSchool of Medicine, Human Genetics Institute, Pontificia Universidad Javeriana, Bogotá, Colombia.
Marcelo GonzálezGroup of Research and Innovation in Vascular Health (GRIVAS Health), Chillan, Chile.
Carlos EscuderoGroup of Research and Innovation in Vascular Health (GRIVAS Health), Chillan, Chile.
Laura Quintero-ArciniegasPerinatal Medicine Seedbed, School of Medicine, Pontificia Universidad Javeriana, Bogotá, Colombia.
Fernanda R GiachiniInstitute of Biological Sciences and Health, Federal University of Mato Grosso, Barra do Garças, Brazil.
Raiany Alves de FreitasInstitute of Biological Sciences, Federal University of Goias, Goiânia, Brazil.
Alicia E DamianoLaboratorio de Biología de la Reproducción, Instituto de Fisiología y Biofísica Bernardo Houssay (IFIBIO)- CONICET- Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Reggie García-RoblesDepartment of Physiological Sciences, School of Medicine, Pontificia Universidad Javeriana, Bogotá, Colombia.
Pontificia Universidad Javeriana · COUniversidade Federal de Goiás · BRConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversity of Bío-Bío · CLUniversity of Concepción · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In December 2019, the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) rapidly spread to become a pandemic. To date, increasing evidence has described the potential negative impact of SARS-CoV-2 infection on pregnant women. Although the pathophysiology of coronavirus disease 2019 (COVID-19) is not entirely understood, there is emerging evidence that it causes a severe systemic inflammatory response associated with vascular alterations that could be of special interest considering some physiological changes in pregnancy. Additionally, these alterations may affect the physiology of the placenta and are associated with pregnancy complications and abnormal histologic findings. On the other hand, data about the vaccine against SARS-CoV-2 are limited, but the risks of administering COVID-19 vaccines during pregnancy appear to be minimal. This review summarizes the current literature on SARSCoV2 virus infection, the development of COVID-19 and its relationship with physiological changes, and angiotensin-converting enzyme 2 (ACE2) function during pregnancy. We have particularly emphasized evidence coming from Latin American countries.

Indexed as

coronavirus in pregnancyCOVID-19placentapregnancyrenin–angiotensin–aldosterone system

Identifiers

PMID35431989
PMCPMC9005899
OpenAlexW4221103960

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.