Evidence map›Paper›PMID 35437982›Full record

ArticleBioconjugate chemistry2022

Exo-Enzymatic Addition of Diazirine-Modified Sialic Acid to Cell Surfaces Enables Photocrosslinking of Glycoproteins.

Nageswari Yarravarapu, Rohit Sai Reddy Konada, Narek Darabedian, Nichole J Pedowitz, Soumya N Krishnamurthy, Matthew R Pratt, Jennifer J Kohler

Abstract read
In one paragraph

Article in Bioconjugate chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nageswari YarravarapuDepartment of Biochemistry, UT Southwestern, Dallas, Texas 75390, United States.ORCID 0000-0002-1975-0077
Rohit Sai Reddy KonadaDepartment of Biochemistry, UT Southwestern, Dallas, Texas 75390, United States.
Narek Darabedian
Nichole J Pedowitz
Soumya N KrishnamurthyDepartment of Biochemistry, UT Southwestern, Dallas, Texas 75390, United States.
Jennifer J KohlerDepartment of Biochemistry, UT Southwestern, Dallas, Texas 75390, United States.ORCID 0000-0001-5373-3329

Funding

Chemical Tools for the Investigation and Manipulation of Protein GlycosylationR01GM125939 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PRATT, MATTHEW ROBERT · 2017 to 2025
$2.4M
NIGMS NIH HHS R01 GM125939
6 · The paper itself

Abstract

Glycan binding often mediates extracellular macromolecular recognition events. Accurate characterization of these binding interactions can be difficult because of dissociation and scrambling that occur during purification and analysis steps. Use of photocrosslinking methods has been pursued to covalently capture glycan-dependent interactions

Indexed as

DiazomethaneN-Acetylneuraminic AcidGlycoproteinsPolysaccharidesSialic AcidsSialyltransferasesDiazomethaneGlycoproteinsN-Acetylneuraminic AcidPolysaccharidesSialic AcidsSialyltransferases

Identifiers

PMID35437982
PMCPMC9426361

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.