Evidence map›Paper›PMID 35437997›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2022

Molecules involved in the development of Barrett's esophagus phenotype in chronic eosinophilic esophagitis.

Sathisha Upparahalli Venkateshaiah, Chandra Sekhar Yadavalli, Hemanth Kumar Kandikattu, Sandeep Kumar, Lokanatha Oruganti, Anil Mishra

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sathisha Upparahalli VenkateshaiahSection of Pulmonary Diseases, John W. Deming Department of Medicine, Tulane Eosinophilic Disorder Center (TEDC), Tulane University School of Medicine, New Orleans, Louisiana.ORCID 0000-0002-0787-0602
Chandra Sekhar YadavalliSection of Pulmonary Diseases, John W. Deming Department of Medicine, Tulane Eosinophilic Disorder Center (TEDC), Tulane University School of Medicine, New Orleans, Louisiana.ORCID 0000-0001-7776-1543
Hemanth Kumar KandikattuSection of Pulmonary Diseases, John W. Deming Department of Medicine, Tulane Eosinophilic Disorder Center (TEDC), Tulane University School of Medicine, New Orleans, Louisiana.ORCID 0000-0001-5114-3341
Sandeep KumarSection of Pulmonary Diseases, John W. Deming Department of Medicine, Tulane Eosinophilic Disorder Center (TEDC), Tulane University School of Medicine, New Orleans, Louisiana.
Lokanatha OrugantiSection of Pulmonary Diseases, John W. Deming Department of Medicine, Tulane Eosinophilic Disorder Center (TEDC), Tulane University School of Medicine, New Orleans, Louisiana.ORCID 0000-0002-1365-1828
Anil MishraSection of Pulmonary Diseases, John W. Deming Department of Medicine, Tulane Eosinophilic Disorder Center (TEDC), Tulane University School of Medicine, New Orleans, Louisiana.ORCID 0000-0003-4266-4684
Tulane University · US

Funding

Role of IL-15 in the Pathogensis of Eosinophilic EsophagitisR01AI080581 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI MISHRA, ANIL · 2009 to 2023
$4.9M
NIAID NIH HHS R01 AI080581
6 · The paper itself

Abstract

This paper aims to investigate the molecules involved in development of Barrett's esophagus (BE) in human eosinophilic esophagitis (EoE). Histopathological, immunohistochemical, real-time PCR Immuno blot, and ELISA analyses are performed to identify the signature genes and proteins involved in the progression of BE in EoE. We detected characteristic features of BE like intermediate columnar-type epithelial cells, induced BE signature genes like

Indexed as

Barrett EsophagusEosinophilic EsophagitisHumansInterleukin-9MucinsPhenotypeInterleukin-9Mucinscolumnar cellseosinophilsepithelial cellsinterleukin-9mucin

Identifiers

PMID35437997
PMCPMC9190763
OpenAlexW4224235792

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.