Evidence map›Paper›PMID 35440585›Full record

ArticleScientific data2022

DOPAMAP, high-resolution images of dopamine 1 and 2 receptor expression in developing and adult mouse brains.

I E Bjerke, E R Cullity, K Kjelsberg, K M Charan, T B Leergaard, J H Kim

Abstract readDataset
In one paragraph

Article in Scientific data, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

I E BjerkeNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.ORCID 0000-0002-2926-6836
E R CullityMental Health Theme, Florey Institute of Neuroscience and Mental Health, Melbourne, Australia.
K KjelsbergNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
K M CharanISN Psychology, Institute for Social Neuroscience, Ivanhoe, Australia.
T B LeergaardNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.ORCID 0000-0001-5965-8470
J H KimMental Health Theme, Florey Institute of Neuroscience and Mental Health, Melbourne, Australia. drjeehyunkim@gmail.com.ORCID 0000-0002-1299-4300

Funding

Department of Health | National Health and Medical Research Council (NHMRC) APP1083309
6 · The paper itself

Abstract

The dopaminergic system undergoes major reorganization during development, a period especially vulnerable to mental disorders. Forebrain neurons expressing dopamine 1 and 2 receptors (D1R and D2R, respectively) play a key role in this system. However, neuroanatomical information about the typical development of these neurons is sparse and scattered across publications investigating one or a few brain regions. We here present a public online collection of microscopic images of immunohistochemically stained serial sections from male and female mice at five stages of development (postnatal day 17 (P17), P25, P35, P49, and adult), showing the distribution of D1R and D2R expressing neurons across the forebrain. All images from adult brains are registered to the Allen Mouse brain Common Coordinate Framework, while images from P17-P35 age groups are registered to spatially modified atlas versions matching the morphology of young brains. This online resource provides microscopic visualization of the developing dopaminergic system in mice, which is suitable as a benchmark reference for performing new experiments and building computational models of the brain.

Indexed as

DopamineProsencephalonReceptors, Dopamine D1Receptors, Dopamine D2AnimalsMiceNeuronsDopamineReceptors, Dopamine D1Receptors, Dopamine D2

Identifiers

PMID35440585
PMCPMC9018709

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.