Evidence map›Paper›PMID 35441140›Full record

ArticleRSC chemical biology2022

Spectroscopic analysis reveals the effect of hairpin loop formation on G-quadruplex structures.

Hengxin Feng, Chun Kit Kwok

Abstract read
In one paragraph

Article in RSC chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hengxin FengDepartment of Chemistry and State Key Laboratory of Marine Pollution, City University of Hong Kong, Kowloon Tong Hong Kong SAR China ckkwok42@cityu.edu.hk +852 3442 0522 +852 3442 6858.ORCID https://orcid.org/0000-0002-8284-9301
Chun Kit KwokDepartment of Chemistry and State Key Laboratory of Marine Pollution, City University of Hong Kong, Kowloon Tong Hong Kong SAR China ckkwok42@cityu.edu.hk +852 3442 0522 +852 3442 6858.ORCID https://orcid.org/0000-0001-9175-8543

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We study and uncover the effect of hairpin structures in loops of G-quadruplexes using spectroscopic methods. Notably, we show that the sequence, structure, and position of the hairpin loop control the spectroscopic properties of long loop G-quadruplexes, and highlight that intrinsic fluorescence can be used to monitor the formation of non-canonical G-quadruplexes.

Identifiers

PMID35441140
PMCPMC8984947

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.