Evidence map›Paper›PMID 35441940›Full record

ReviewMolecular biology reports2022

Potentials of ketogenic diet against chronic kidney diseases: pharmacological insights and therapeutic prospects.

Sushmita Kundu, Khandkar Shaharina Hossain, Akhi Moni, Md Sarwar Zahan, Md Masudur Rahman, Md Jamal Uddin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. The Biochemical Role of Bitter Melon (Food science & nutrition · 2026
    Article
  4. Review
  5. Review
  6. Diet as a treatment for chronic kidney disease.Childhood kidney diseases · 2024
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sushmita Kundu *ABEx Bio-Research Center, East Azampur, Dhaka, 1230, Bangladesh.
Khandkar Shaharina Hossain *ABEx Bio-Research Center, East Azampur, Dhaka, 1230, Bangladesh.
Akhi MoniABEx Bio-Research Center, East Azampur, Dhaka, 1230, Bangladesh.
Md Sarwar ZahanABEx Bio-Research Center, East Azampur, Dhaka, 1230, Bangladesh.
Md Masudur RahmanDepartment of Pathology, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet, 3100, Bangladesh.
Md Jamal UddinABEx Bio-Research Center, East Azampur, Dhaka, 1230, Bangladesh. hasan800920@gmail.com.ORCID http://orcid.org/0000-0003-2911-3255
Ewha Womans University · KRSylhet Agricultural University · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is a worldwide public health concern. Nutritional interventions become a primary concern in managing various diseases, including CKD. Ketogenic diets (KD) are a popular diet and an increasingly used diet for weight loss. MAIN BODY: With the increasing cases of CKD, KD has been proposed as a treatment by many scientists. Several studies have shown that KD can slow down the progression rate of renal abnormalities. Also, this diet is regarded as a safe route for managing CKD. CKD is generally associated with increased inflammation, oxidative stress, fibrosis, autophagy dysfunction, and mitochondrial dysfunction, while all of these can be attenuated by KD. The protective effect of KD is mainly mediated through inhibition of ROS, NF-κB, and p62 signaling.

conclusionsIt is suggested that KD could be considered a new strategy for managing and treating CKD more carefully. This review explores the potential of KD on CKD and the mechanism involved in KD-mediated kidney protection.

Indexed as

Diet, KetogenicRenal Insufficiency, ChronicHumansNF-kappa BOxidative StressReactive Oxygen SpeciesNF-kappa BReactive Oxygen SpeciesCKDKetogenic dietOxidative stressPharmacological insightsTherapeutic promises

Identifiers

PMID35441940
OpenAlexW4224255027

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.