Evidence map›Paper›PMID 35443705›Full record

ArticleJournal of physiological anthropology2022

Brown adipose tissue thermogenesis among a small sample of reindeer herders from sub-Arctic Finland.

Cara Ocobock, Päivi Soppela, Minna Turunen, Ville Stenbäck, Karl-Heinz Herzig

Open access · goldAbstract read
In one paragraph

Article in Journal of physiological anthropology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Neandertal Cold Adaptation: Technological, Anatomical, and Physiological Responses to Cold Stress in One of Our Closest Fossil Relatives.American journal of human biology : the official journal of the Human Biology Council · 2025
    Article
  4. Review
  5. Review
  6. Indication of mixed glucose and fatty acid use by inferred brown adipose tissue activity in Samoans.American journal of human biology : the official journal of the Human Biology Council · 2024
    Article
  7. Article
  8. To the extreme! How biological anthropology can inform exercise physiology in extreme environments.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Cara OcobockDepartment of Anthropology, University of Notre Dame, Corbett Family Hall 296, Notre Dame, IN, 46556, USA. cocobock@nd.edu.ORCID http://orcid.org/0000-0002-6949-2029
Päivi SoppelaUniversity of Lapland, Arctic Centre, Rovaniemi, Finland.
Minna TurunenUniversity of Lapland, Arctic Centre, Rovaniemi, Finland.
Ville StenbäckResearch Unit of Biomedicine, Medical Research Center, Faculty of Medicine, University of Oulu, and Oulu University Hospital, Oulu, Finland.
Karl-Heinz HerzigResearch Unit of Biomedicine, Medical Research Center, Faculty of Medicine, University of Oulu, and Oulu University Hospital, Oulu, Finland.
University of Lapland · FIOulu University Hospital · FIPoznan University of Medical Sciences · PLUniversity of Notre Dame · US

Funding

National Science Foundation 78846
6 · The paper itself

Abstract

introductionInterest in human physiological responses to cold stress have seen a resurgence in recent years with a focus on brown adipose tissue (BAT), a mitochondria dense fat specialized for heat production. However, a majority of the work examining BAT has been conducted among temperate climate populations.

methodsTo expand our understanding of BAT thermogenesis in a cold climate population, we measured, using indirect calorimetry and thermal imaging, metabolic rate and body surface temperatures of BAT-positive and BAT-negative regions at room temperature, and mild cold exposure of resting participants from a small sample of reindeer herders (N = 22, 6 females) from sub-Arctic Finland.

resultsWe found that most herders experienced a significant mean 8.7% increase in metabolic rates, preferentially metabolized fatty acids, and maintained relatively warmer body surface temperatures at the supraclavicular region (known BAT location) compared to the sternum, which has no associated BAT. These results indicate that the herders in this sample exhibit active BAT thermogenesis in response to mild cold exposure.

conclusionsThis study adds to the rapidly growing body of work looking at the physiological and thermoregulatory significance of BAT and the important role it may play among cold stressed populations.

Indexed as

ReindeerAdipose Tissue, BrownAnimalsCold TemperatureFemaleFinlandHumansMaleThermogenesisBrown adipose tissueCold stressMetabolismNon-shivering thermogenesisRespiratory quotient

Identifiers

PMID35443705
PMCPMC9022279
OpenAlexW4224300057

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.