Evidence map›Paper›PMID 35446863›Full record

SynthesisPloS one2022

Supplementary education can improve the rate of adequate bowel preparation in outpatients: A systematic review and meta-analysis based on randomized controlled trials.

Shicheng Peng, Sixu Liu, Jiaming Lei, Wensen Ren, Lijun Xiao, Xiaolan Liu, Muhan Lü, Kai Zhou

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shicheng PengDepartment of Gastroenterology, Affiliated Hospital of Southwest Medical University, Luzhou, China.
Sixu LiuDepartment of Gastroenterology, Affiliated Hospital of Southwest Medical University, Luzhou, China.
Jiaming LeiDepartment of Gastroenterology, Affiliated Hospital of Southwest Medical University, Luzhou, China.
Wensen RenDepartment of Gastroenterology, Affiliated Hospital of Southwest Medical University, Luzhou, China.
Lijun XiaoDepartment of Gastroenterology, Affiliated Hospital of Southwest Medical University, Luzhou, China.
Xiaolan LiuDepartment of Gastroenterology, Affiliated Hospital of Southwest Medical University, Luzhou, China.
Muhan LüDepartment of Gastroenterology, Affiliated Hospital of Southwest Medical University, Luzhou, China.
Kai ZhouDepartment of Emergency, Affiliated Hospital of Southwest Medical University, Luzhou, China.ORCID 0000-0002-0180-150X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColonoscopy is widely used for the screening, diagnosis and treatment of intestinal diseases. Adequate bowel preparation is a prerequisite for high-quality colonoscopy. However, the rate of adequate bowel preparation in outpatients is low. Several studies on supplementary education methods have been conducted to improve the rate of adequate bowel preparation in outpatients. However, the controversial results presented encourage us to perform this meta-analysis.

methodAccording to the PRISMA statement (2020), the meta-analysis was registered on PROSPERO. We searched all studies up to August 28, 2021, in the three major electronic databases of PubMed, Web of Science and Cochrane Library. The primary outcome was adequate bowel preparation rate, and the secondary outcomes included bowel preparation quality score, polyp detection rate, adenoma detection rate, cecal intubation time, withdrawal time, nonattendance rate and willingness to repeat rate. If there was obvious heterogeneity, the funnel plot combined with Egger's test, meta-regression analysis, sensitivity analysis and subgroup analysis were used to detect the source of heterogeneity. RevMan 5.3 and Stata 17.0 software were used for statistical analysis.

resultsA total of 2061 records were retrieved, and 21 full texts were ultimately included in the analysis. Our meta-analysis shows that supplementary education can increase the rate of adequate bowel preparation for outpatients (79.9% vs 72.9%, RR = 1.14, 95% CI: 1.08-1.20, I2 = 87%, p<0.00001). Supplementary education shortened the withdrawal time (MD: -0.80, 95% CI: -1.54 to -0.05, p = 0.04) of outpatients, increased the Boston Bowel Preparation Scale (MD: 0.40, 95% CI: 0.36 to 0.44, p<0.00001), reduced the Ottawa Bowel Preparation Scale (MD: -1.26, 95% CI: -1.66 to -0.86, p<0.00001) and increased the willingness to repeat (91.9% vs 81.4%, RR:1.14, 95% CI: 1.04 to 1.25, p = 0.004).

conclusionSupplementary education for outpatients based on the standard of care can significantly improve the quality of bowel preparation.

Indexed as

AdenomaColonoscopyCatharticsCecumHumansOutpatientsRandomized Controlled Trials as TopicCathartics

Identifiers

PMID35446863
PMCPMC9023061

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.