Evidence map›Paper›PMID 35448303›Full record

ArticleBiosensors2022

Fiber-Enhanced Stimulated Raman Scattering and Sensitive Detection of Dilute Solutions.

Li Guo, Jing Huang, Yaxin Chen, Bohan Zhang, Minbiao Ji

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Li GuoState Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan University, Shanghai 200433, China.
Jing HuangState Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan University, Shanghai 200433, China.ORCID 0000-0003-0194-7549
Yaxin ChenState Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan University, Shanghai 200433, China.
Bohan ZhangState Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan University, Shanghai 200433, China.
Minbiao JiState Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan University, Shanghai 200433, China.ORCID 0000-0002-9066-4008
Fudan University · CN

Funding

National Natural Science Foundation of China 61975033
6 · The paper itself

Abstract

Stimulated Raman scattering (SRS) is known to gain coherent amplification of molecular vibrations that allow for rapid and label-free chemical imaging in the microscopy setting. However, the tightly focused laser spot has limited the detection sensitivity, partly due to the tiny interaction volume. Here, we report the use of metal-lined hollow-core fiber (MLHCF) to improve the sensitivity of SRS in sensing dilute solutions by extending the light-matter interaction volume through the fiber waveguide. With a focusing lens (100 mm FL) and 320 μm diameter fiber, we demonstrated an optimum enhancement factor of ~20 at a fiber length of 8.3 cm. More importantly, the MLHCF exhibited a significantly suppressed cross-phase modulation (XPM) background, enabling the detection of ~0.7 mM DMSO in water. Furthermore, the relationship between fiber length and SRS signal could be well explained theoretically. The fiber-enhanced SRS (FE-SRS) method may be further optimized and bears potential in the sensitive detection of molecules in the solution and gas phases.

Indexed as

MicroscopySpectrum Analysis, RamanLasersbiosensingfiber enhancedspectroscopystimulated Raman scattering

Identifiers

PMID35448303
PMCPMC9028131
OpenAlexW4223903670

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.