ArticleMetabolites2022
Gut Microbiota and Serum Metabolome in Elite Cross-Country Skiers: A Controlled Study.
Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Physical activity, sedentary behavior and microbiome: A systematic review and meta-analysis.Journal of science and medicine in sport · 2024Pooled it
- Signatures in the gut microbiome of German elite athletes: insights from a matched-subgroup analysis.mSystems · 2026Trial
- Lipid metabolism, microglia, and stroke.Neural regeneration research · 2026Article
- The Athlete Gut Microbiome: A Narrative Review of Multi-Omics Insights and Next-Generation Probiotic Strategies.Nutrients · 2025Review
- Gut microbiota-derived butyrate enhances exercise-induced bone mineral density in humans.Mechanobiology in medicine · 2025Article
- Physical Exercise and the Gut Microbiome: A Bidirectional Relationship Influencing Health and Performance.Nutrients · 2024Review
- Dietary Patterns, Gut Microbiota and Sports Performance in Athletes: A Narrative Review.Nutrients · 2024Review
- Relationships between Habitual Polyphenol Consumption and Gut Microbiota in the INCLD Health Cohort.Nutrients · 2024Article
- The Impact of Physical Effort on the Gut Microbiota of Long-Distance Fliers.Microorganisms · 2023Article
- Exercise Metabolome: Insights for Health and Performance.Metabolites · 2023Review
- The Impact of Nutrition, Physical Activity, Beneficial Microbes, and Fecal Microbiota Transplant for Improving Health.Life (Basel, Switzerland) · 2023Review
- A Bibliometric Analysis on the Research Trend of Exercise and the Gut Microbiome.Microorganisms · 2023Review
- Potential ofFrontiers in microbiology · 2023Review
- Gut microbiota and metabolite variations in a migraine mouse model.Frontiers in cellular and infection microbiology · 2023Article
- Is There a Universal Endurance Microbiota?Microorganisms · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Exercise has been shown to affect gut the microbiome and metabolic health, with athletes typically displaying a higher microbial diversity. However, research on the gut microbiota and systemic metabolism in elite athletes remains scarce. In this study, we compared the gut microbiota profiles and serum metabolome of national team cross-country skiers at the end of an exhausting training and competitive season to those of normally physically-active controls. The gut microbiota were analyzed using 16S rRNA amplicon sequencing. Serum metabolites were analyzed using nuclear magnetic resonance. Phylogenetic diversity and the abundance of several mucin-degrading gut microbial taxa, including Akkermansia, were lower in the athletes. The athletes had a healthier serum lipid profile than the controls, which was only partly explained by body mass index. Butyricicoccus associated positively with HDL cholesterol, HDL2 cholesterol and HDL particle size. The Ruminococcus torques group was less abundant in the athlete group and positively associated with total cholesterol and VLDL and LDL particles. We found the healthier lipid profile of elite athletes to co-occur with known health-beneficial gut microbes. Further studies should elucidate these links and whether athletes are prone to mucin depletion related microbial changes during the competitive season.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.