Evidence map›Paper›PMID 35448969›Full record

ArticleBMC cardiovascular disorders2022

Glycemic status, non-traditional risk and left ventricular structure and function in the Jackson Heart Study.

Chizobam Ani, David Shavlik, Synnove Knutsen, Islam Abudayyeh, Jimmie Banta, Emily O'Brien, Robert J Mentz, Alain G Bertoni, Gary Fraser

Open access · goldAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Chizobam AniLoma Linda University (LLU), Loma Linda, USA. cani@llu.edu.ORCID 0000-0002-6125-5475
David ShavlikLoma Linda University (LLU), Loma Linda, USA.
Synnove KnutsenLoma Linda University (LLU), Loma Linda, USA.
Islam AbudayyehLoma Linda University (LLU), Loma Linda, USA.
Jimmie BantaLoma Linda University (LLU), Loma Linda, USA.
Emily O'BrienDuke University, Durham, USA.
Robert J MentzDuke University, Durham, USA.
Alain G BertoniWake Forest School of Medicine (Department of Epidemiology and Prevention), Winston-Salem, USA.
Gary FraserLoma Linda University (LLU), Loma Linda, USA.
Loma Linda University · USDuke University · USUniversity of California, Los Angeles · USWake Forest University · US

Funding

NHLBI NIH HHS HHSN268201800010INHLBI NIH HHS HHSN268201800011CNHLBI NIH HHS HHSN268201800011INHLBI NIH HHS HHSN268201800012CNHLBI NIH HHS HHSN268201800012INHLBI NIH HHS HHSN268201800014CNHLBI NIH HHS HHSN268201800014INHLBI NIH HHS HHSN268201800015INIMHD NIH HHS HHSN268201800013I
6 · The paper itself

Abstract

backgroundLeft ventricular structure and function abnormalities may be an early marker of cardiomyopathy among African Americans with diabetes (DM) even in the absence of coronary artery disease (CAD), arrhythmia, valvular heart disease and end-stage renal disease (ESRD). This study examined the association of prediabetes (PDM), DM and HbA1c with left ventricular structure and function among Jackson Heart Study (JHS) participants without traditional risk factors.

methodsRetrospective cross-sectional analyses of the association of PDM, DM and HbA1c with, left ventricular ejection fraction (LV EF), fractional shortening (LV FS), stroke volume index (SVI), cardiac index (CI), left ventricular end diastolic volume index (LVEDVI), left ventricular end systolic volume index (LVESVI), relative wall thickness (RWT), myocardial contraction fraction (MCF) and left ventricular mass index (LVMI). The study was conducted in 2234 adult JHS participants without preexisting CAD, arrhythmia, valvular heart disease or ESRD. Statistical analyses included descriptive, univariate and covariate adjusted linear regression analyses. Sensitivity analyses to explore the impact of hypertension on study outcomes were also carried out.

resultsDM compared with no DM was associated with lower, SVI (- 0.96 ml/m

conclusionsGlycemic status is associated with important left ventricular structure and function changes among African Americans without prior CAD, arrhythmia, valvular heart disease and ESRD. Longitudinal studies may further elucidate these relationships.

Indexed as

Coronary Artery DiseaseHeart Valve DiseasesKidney Failure, ChronicAdultCross-Sectional StudiesFemaleGlycated HemoglobinHumansLongitudinal StudiesMaleRetrospective StudiesStroke VolumeVentricular Function, LeftGlycated HemoglobinAfrican AmericanDiabetesDiabetic cardiomyopathyLeft ventricular structure

Identifiers

PMID35448969
PMCPMC9022283
OpenAlexW4224259715

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.