Evidence map›Paper›PMID 35451227›Full record

ArticleChemMedChem2022

Investigating the Role of Sulfate Groups for the Binding of Gd

Patrick Werner, Patrick Schuenke, Oxana Krylova, Heike Nikolenko, Matthias Taupitz, Leif Schröder

Open access · hybridAbstract read
In one paragraph

Article in ChemMedChem, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  4. Thermodynamics of calcium binding to heparin: Implications of solvation and water structuring for polysaccharide biofunctions.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Patrick WernerDivision of Translational Molecular Imaging, Deutsches Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.ORCID 0000-0002-8970-7090
Patrick SchuenkeMolecular Imaging / Molecular Biophysics, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Str. 10, 13125, Berlin, Germany.ORCID 0000-0002-3179-4830
Oxana KrylovaMolecular Imaging / Molecular Biophysics, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Str. 10, 13125, Berlin, Germany.ORCID 0000-0001-5821-7606
Heike NikolenkoMolecular Imaging / Molecular Biophysics, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Str. 10, 13125, Berlin, Germany.
Matthias TaupitzDepartment of Radiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.ORCID 0000-0002-2994-8263
Leif SchröderDivision of Translational Molecular Imaging, Deutsches Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.ORCID 0000-0003-4901-0325
German Cancer Research Center · DELeibniz-Forschungsinstitut für Molekulare Pharmakologie · DEHumboldt-Universität zu Berlin · DEPhysikalisch-Technische Bundesanstalt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycosaminoglycans (GAGs) are highly negatively charged macromolecules with a large cation binding capacity, but their interaction potential with exogeneous Gd

Indexed as

GlycosaminoglycansSulfatesChelating AgentsContrast MediaHeparinMagnetic Resonance ImagingChelating AgentsContrast MediaGlycosaminoglycansHeparinSulfateschelationgadoliniumGBCAglycosaminoglycansMRI contrast agent

Identifiers

PMID35451227
PMCPMC9400987
OpenAlexW4224250549

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.