ArticleDevelopmental psychobiology2022
Aperiodic electrophysiological activity in preterm infants is linked to subsequent autism risk.
Article in Developmental psychobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- A Systematic Review of Aperiodic Neural Activity in Clinical Investigations.The European journal of neuroscience · 2025Pooled it
- Aperiodic and Hurst EEG exponents across early human brain development: A systematic review.Developmental cognitive neuroscience · 2024Pooled it
- Cannabidiol blood metabolite levels after cannabidiol treatment are associated with broadband EEG changes and improvements in visuomotor and non-verbal cognitive abilities in boys with autism requiring higher levels of support.Translational psychiatry · 2026Trial
- Task-Related Aperiodic EEG (1/f) Activity in Autism.Autism research : official journal of the International Society for Autism Research · 2026Article
- Long-term reliability and stability of parameterized resting state EEG: evidence from a five-year follow-up.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Characterization of aperiodic and theta activity in preterm infants using EEG: Insights into cerebral maturation and inter-individual variability.Developmental cognitive neuroscience · 2026Article
- Aperiodic Dynamics of Cell Assemblies Recruited for L1 and L2 Processing of FrenchBrain sciences · 2026Article
- Asymmetric neural dynamics of visuospatial attention in autism spectrum disorder.bioRxiv : the preprint server for biology · 2026Article
- Altered spectral patterns of aperiodic electroencephalography in autism.Psychiatry and clinical neurosciences · 2026Article
- Aperiodic and periodic neural activity during sleep in autism spectrum disorders.BMC medicine · 2026Article
- Cortical markers of excitation/inhibition balance are associated with sensory responsivity from infancy in longitudinal cohorts enriched for autism and ADHD.Translational psychiatry · 2025Article
- Cannabidiol blood metabolite levels after cannabidiol treatment are associated with broadband EEG changes and improvements in visuomotor and non-verbal cognitive abilities in boys with autism requiring higher levels of support.medRxiv : the preprint server for health sciences · 2025Article
- The development of aperiodic neural activity in the human brain.Nature human behaviour · 2025Article
- Resting State Electroencephalography (EEG) Reveals Atypical Oscillatory Power in Children With Development Coordination Disorder (DCD).Psychophysiology · 2025Article
- Resting Electroencephalography Microstates and Alpha Power Modulation in Preschool-Aged Children with Autism Spectrum Disorder.Brain sciences · 2025Article
- Time-Resolved Aperiodic and Oscillatory Dynamics during Human Visual Memory Encoding.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Oscillatory But Not Aperiodic Frontal Brain Activity Predicts the Development of Executive Control From Infancy to Toddlerhood.Developmental science · 2025Article
- Maternal Gestational Diabetes Mellitus (GDM) Moderates the Association Between Birth Weight and EEG Power in Healthy Term-Age Newborns.Developmental psychobiology · 2025Article
- Exploring neurodevelopment through oscillatory and aperiodic EEG activity: methodological and clinical consideration.Frontiers in human neuroscience · 2025Review
- Neurophysiological avenues to better conceptualizing adaptive cognition.Communications biology · 2024Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
Approximately 7% of preterm infants receive an autism spectrum disorder (ASD) diagnosis. Yet, there is a significant gap in the literature in identifying prospective markers of neurodevelopmental risk in preterm infants. The present study examined two electroencephalography (EEG) parameters during infancy, absolute EEG power and aperiodic activity of the power spectral density (PSD) slope, in association with subsequent autism risk and cognitive ability in a diverse cohort of children born preterm in South Africa. Participants were 71 preterm infants born between 25 and 36 weeks gestation (34.60 ± 2.34 weeks). EEG was collected during sleep between 39 and 41 weeks postmenstrual age adjusted (40.00 ± 0.42 weeks). The Bayley Scales of Infant Development and Brief Infant Toddler Social Emotional Assessment (BITSEA) were administered at approximately 3 years of age adjusted (34 ± 2.7 months). Aperiodic activity, but not the rhythmic oscillatory activity, at multiple electrode sites was associated with subsequent increased autism risk on the BITSEA at three years of age. No associations were found between the PSD slope or absolute EEG power and cognitive development. Our findings highlight the need to examine potential markers of subsequent autism risk in high-risk populations other than infants at familial risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.