Evidence map›Paper›PMID 35453209›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Antibiotic Prescription Patterns in the Paediatric Primary Care Setting before and after the COVID-19 Pandemic in Italy: An Analysis Using the AWaRe Metrics.

Elisa Barbieri, Cecilia Liberati, Anna Cantarutti, Costanza Di Chiara, Angela Lupattelli, Michael Sharland, Carlo Giaquinto, Yingfen Hsia, Daniele Doná

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

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  13. Antibiotics Use in Primary Care during COVID-19.Antibiotics (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Article
  16. Predicting the Physician's Specialty Using a Medical Prescription Database.Computational and mathematical methods in medicine · 2022
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Elisa BarbieriDivision of Paediatric Infectious Diseases, Department for Women's and Children's Health, University of Padua, 35100 Padua, Italy.ORCID 0000-0003-0850-8784
Cecilia LiberatiDivision of Paediatric Infectious Diseases, Department for Women's and Children's Health, University of Padua, 35100 Padua, Italy.ORCID 0000-0002-0821-5757
Anna CantaruttiUnit of Biostatistics, Epidemiology and Public Health, Department of Statistics and Quantitative Methods, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0002-3700-780X
Costanza Di ChiaraDivision of Paediatric Infectious Diseases, Department for Women's and Children's Health, University of Padua, 35100 Padua, Italy.ORCID 0000-0002-3586-0612
Angela LupattelliPharmacoEpidemiology and Drug Safety Research Group, Department of Pharmacy, and PharmaTox Strategic Research Initiative, University of Oslo, 0316 Oslo, Norway.ORCID 0000-0002-8787-3183
Michael SharlandPharmacoEpidemiology and Drug Safety Research Group, Department of Pharmacy, and PharmaTox Strategic Research Initiative, University of Oslo, 0316 Oslo, Norway.
Carlo GiaquintoDivision of Paediatric Infectious Diseases, Department for Women's and Children's Health, University of Padua, 35100 Padua, Italy.
Yingfen HsiaCentre for Neonatal and Paediatric Infection, St George's University of London, London SW17 0RE, UK.ORCID 0000-0002-7955-852X
Daniele DonáDivision of Paediatric Infectious Diseases, Department for Women's and Children's Health, University of Padua, 35100 Padua, Italy.
University of Padua · ITUniversity of Oslo · NOQueen's University Belfast · GBUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The containment measures following COVID-19 pandemic drastically reduced airway infections, but they also limited the access of patients to healthcare services. We aimed to assess the antibiotic prescription patterns in the Italian paediatric primary care setting before and after the containment measures implementation. For this retrospective analysis, we used a population database, Pedianet, collecting data of patients aged 0-14 years enrolled with family paediatricians (FP) from March 2019 to March 2021. Antibiotic prescriptions were classified according to WHO AWaRe classification. An interrupted time series evaluating the impact of the containment measures implementation on the monthly antibiotic index, on the access to watch index, and on the amoxicillin to co-amoxiclav index stratified by diagnosis was performed. Overall, 121,304 antibiotic prescriptions were retrieved from 134 FP, for a total of 162,260 children. From March 2020, the antibiotic index dropped by more than 80% for respiratory infections. The Access to Watch trend did not change after the containment measures, reflecting the propensity to prescribe more broad-spectrum antibiotics for respiratory infections even during the pandemic. Similarly, co-amoxiclav was prescribed more often than amoxicillin alone for all the diagnoses, with a significant variation in the trend slope for upper respiratory tract infections prescriptions.

Indexed as

antibioticsAWaRe classificationCOVID-19 pandemic

Identifiers

PMID35453209
PMCPMC9025823
OpenAlexW4220809785

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.