Evidence mapPaperPMID 35453319Full record

ReviewAntioxidants (Basel, Switzerland)2022

Function, Mechanism, and Application of Plant Melatonin: An Update with a Focus on the Cereal Crop, Barley (

Xinxing Yang, Jie Chen, Yuan Ma, Minhua Huang, Ting Qiu, Hongwu Bian, Ning Han, Junhui Wang

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Review
  3. Preventive Effects ofInternational journal of molecular sciences · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Biomolecules · 2023
    Article
  12. Melatonin Role in Plant Growth and Physiology under Abiotic Stress.International journal of molecular sciences · 2023
    Review
  13. Article
  14. Review
  15. Article
  16. Human Naa50 Shows SerotoninAntioxidants (Basel, Switzerland) · 2023
    Article
  17. Melatonin Involved in Protective Effects against Cadmium Stress inInternational journal of molecular sciences · 2023
    Article
  18. Review
  19. Article
  20. Functional Characterization of ArylalkylamineAntioxidants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xinxing YangInstitute of Genetics and Regenerative Biology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Jie ChenInstitute of Genetics and Regenerative Biology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Yuan MaInstitute of Genetics and Regenerative Biology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Minhua HuangInstitute of Genetics and Regenerative Biology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Ting QiuSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Hongwu BianInstitute of Genetics and Regenerative Biology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Ning HanInstitute of Genetics and Regenerative Biology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Junhui WangInstitute of Genetics and Regenerative Biology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-6333-0096
Zhejiang University · CNHangzhou Normal University · CN

Funding

China Agriculture Research System project CARS-05-05ANational Natural Science Foundation of China no. 31971932 to H.B.National Natural Science Foundation of China no. 32000363 to T.Q.Zhejiang Provincial Natural Science Foundation LY18C020001
6 · The paper itself

Abstract

Melatonin is a multiple-function molecule that was first identified in animals and later in plants. Plant melatonin regulates versatile processes involved in plant growth and development, including seed germination, root architecture, flowering time, leaf senescence, fruit ripening, and biomass production. Published reviews on plant melatonin have been focused on two model plants: (1) Arabidopsis and (2) rice, in which the natural melatonin contents are quite low. Efforts to integrate the function and the mechanism of plant melatonin and to determine how plant melatonin benefits human health are also lacking. Barley is a unique cereal crop used for food, feed, and malt. In this study, a bioinformatics analysis to identify the genes required for barley melatonin biosynthesis was first performed, after which the effects of exogenous melatonin on barley growth and development were reviewed. Three integrated mechanisms of melatonin on plant cells were found: (1) serving as an antioxidant, (2) modulating plant hormone crosstalk, and (3) signaling through a putative plant melatonin receptor. Reliable approaches for characterizing the function of barley melatonin biosynthetic genes and to modulate the melatonin contents in barley grains are discussed. The present paper should be helpful for the improvement of barley production under hostile environments and for the reduction of pesticide and fungicide usage in barley cultivation. This study is also beneficial for the enhancement of the nutritional values and healthcare functions of barley in the food industry.

Indexed as

antioxidantbarley (Hordeum vulgare L.)CAND2/PMTR1melatonin biosynthesisplant stress response

Identifiers

PMID35453319
PMCPMC9028855
OpenAlexW4221027302

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.