Evidence map›Paper›PMID 35453708›Full record

ArticleBiology2022

Plasma miRNA Profile of Crohn's Disease and Rheumatoid Arthritis Patients.

Tatiana D Saccon, Joseph M Dhahbi, Augusto Schneider, Yury O Nunez Lopez, Ahmad Qasem, Marcelo B Cavalcante, Lauren K Sing, Saleh A Naser, Michal M Masternak

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The Role of microRNAs in Inflammatory Bowel Disease.International journal of molecular sciences · 2025
    Review
  4. miR-574-5p in epigenetic regulation and Toll-like receptor signaling.Cell communication and signaling : CCS · 2024
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Tatiana D SacconCentro de Desenvolvimento Tecnológico, Universidade Federal de Pelotas, Pelotas 96010-610, Brazil.ORCID 0000-0001-5328-4922
Joseph M DhahbiDepartment of Medical Education, School of Medicine, California University of Science & Medicine, San Bernardino, CA 92324, USA.
Augusto SchneiderFaculdade de Nutrição, Universidade Federal de Pelotas, Pelotas 96010-610, Brazil.
Yury O Nunez LopezTranslational Research Institute, AdventHealth, Orlando, FL 32804, USA.
Ahmad QasemBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0003-3740-6963
Marcelo B CavalcanteBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0001-9943-9731
Lauren K SingDepartment of Medical Education, School of Medicine, California University of Science & Medicine, San Bernardino, CA 92324, USA.
Saleh A NaserBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0001-9222-4527
Michal M MasternakBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32816, USA.
University of Central Florida · USCalifornia State University, San Bernardino · USAdventHealth Orlando · USUniversidade Federal de Pelotas · BR

Funding

NIH/NIA grants (MM) R15 AG059190, R56 AG061414
6 · The paper itself

Abstract

Crohn's disease (CD) and rheumatoid arthritis (RA) are immune mediated inflammatory diseases. Several studies indicate a role for microRNAs (miRNAs) in the pathogenesis of a variety of autoimmune diseases, including CD and RA. Our study's goal was to investigate circulating miRNAs in CD and RA patients to identify potential new biomarkers for early detection and personalized therapeutic approaches for autoimmune diseases. For this study, subjects with CD (

Indexed as

autoimmune diseasesCrohn’s diseaseinflammationmicroRNAsrheumatoid arthritis

Identifiers

PMID35453708
PMCPMC9033111
OpenAlexW4220959251

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.