Evidence map›Paper›PMID 35454138›Full record

ReviewBiomolecules2022

Factors Influencing Gallstone Formation: A Review of the Literature.

Hao Sun, Jonathan Warren, James Yip, Yu Ji, Shaolong Hao, Wei Han, Yuchuan Ding

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 7 pooled it
23.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 7 syntheses or guidelines pooled it, 173 citations in OpenAlex.

  1. Pooled it
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  8. Review
  9. Article
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  12. Article
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  14. Article
  15. Gut Microbiome Dysbiosis Promotes Gallstone Formation via Bile Acid Metabolic Disorder: A Multiomics Study.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Hao SunCentral Laboratories, Beijing Luhe Clinical Institute, Capital Medical University, Beijing 101199, China.
Jonathan WarrenDepartment of Neurosurgery, Wayne State University School of Medicine, Detroit, MI 48201, USA.ORCID 0000-0002-7205-7191
James YipDepartment of Pathology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96831, USA.
Yu JiCentral Laboratories, Beijing Luhe Clinical Institute, Capital Medical University, Beijing 101199, China.
Shaolong HaoDepartment of General Surgery, Beijing Luhe Clinical Institute, Capital Medical University, Beijing 101199, China.
Wei HanCentral Laboratories, Beijing Luhe Clinical Institute, Capital Medical University, Beijing 101199, China.
Yuchuan DingDepartment of Neurosurgery, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Beijing Luhe Hospital Affiliated to Capital Medical University · CNWayne State University · USUniversity of Hawaiʻi at Mānoa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gallstone disease is a common pathology of the digestive system with nearly a 10-20% incidence rate among adults. The mainstay of treatment is cholecystectomy, which is commonly associated with physical pain and may also seriously affect a patient's quality of life. Clinical research suggests that cholelithiasis is closely related to the age, gender, body mass index, and other basic physical characteristics of patients. Clinical research further suggests that the occurrence of cholelithiasis is related to obesity, diabetes, non-alcoholic fatty liver, and other diseases. For this reason, we reviewed the following: genetic factors; excessive liver cholesterol secretion (causing cholesterol supersaturation in gallbladder bile); accelerated growth of cholesterol crystals and solid cholesterol crystals; gallbladder motility impairment; and cardiovascular factors. Herein, we summarize and analyze the causes and mechanisms of cholelithiasis, discuss its correlation with the pathogenesis of related diseases, and discuss possible mechanisms.

Indexed as

GallstonesAdultBileBile Acids and SaltsCholesterolHumansQuality of LifeBile Acids and SaltsCholesterolbile acidscardiovascular diseasediabetesgallstone diseasenon-alcoholic fatty liverobesity

Identifiers

PMID35454138
PMCPMC9026518
OpenAlexW4224290461

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.