Evidence map›Paper›PMID 35455722›Full record

ArticleJournal of personalized medicine2022

Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia: CARE-FH Protocol.

Laney K Jones, Marc S Williams, Ilene G Ladd, Dylan Cawley, Shuping Ge, Jing Hao, Dina Hassen, Yirui Hu, H Lester Kirchner, Maria Kobylinski and 9 more

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Laney K JonesHeart and Vascular Institute, Geisinger, Danville, PA 17821, USA.ORCID 0000-0002-6182-5634
Marc S WilliamsGenomic Medicine Institute, Geisinger, Danville, PA 17821, USA.ORCID 0000-0001-6165-8701
Ilene G LaddGenomic Medicine Institute, Geisinger, Danville, PA 17821, USA.
Dylan CawleyGenomic Medicine Institute, Geisinger, Danville, PA 17821, USA.
Shuping GeDepartment of Pediatrics, Geisinger, Danville, PA 17821, USA.
Jing HaoDepartment of Population Health Sciences, Geisinger, Danville, PA 17821, USA.ORCID 0000-0001-9332-3842
Dina HassenDepartment of Population Health Sciences, Geisinger, Danville, PA 17821, USA.
Yirui HuDepartment of Population Health Sciences, Geisinger, Danville, PA 17821, USA.
H Lester KirchnerDepartment of Population Health Sciences, Geisinger, Danville, PA 17821, USA.
Maria KobylinskiDepartment of Community Medicine, Geisinger, Danville, PA 17821, USA.
Michael G LeskoHeart and Vascular Institute, Geisinger, Danville, PA 17821, USA.
Matthew C NelsonDepartment of Pediatrics, Geisinger, Danville, PA 17821, USA.
Alanna K RahmGenomic Medicine Institute, Geisinger, Danville, PA 17821, USA.ORCID 0000-0003-2513-9298
David D RolstonDepartment of Internal Medicine, Geisinger, Danville, PA 17821, USA.ORCID 0000-0002-8707-949X
Katrina M RomagnoliDepartment of Translational Data Science and Informatics, Geisinger, Danville, PA 17821, USA.
Tyler J SchubertGenomic Medicine Institute, Geisinger, Danville, PA 17821, USA.
Timothy C ShueyDepartment of Internal Medicine, Geisinger, Danville, PA 17821, USA.ORCID 0000-0003-4864-3788
Amy C SturmHeart and Vascular Institute, Geisinger, Danville, PA 17821, USA.
Samuel S GiddingGenomic Medicine Institute, Geisinger, Danville, PA 17821, USA.

Funding

Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia: CARE-FHR33HL161775 · NHLBI · GEISINGER CLINIC · PI Samuel S Gidding · 2023 to 2026
$2.9M
Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia: CARE-FHR61HL161775 · NHLBI · GEISINGER CLINIC · PI GIDDING, SAMUEL S, JONES, LANEY K · 2022 to 2022
$423k
NHLBI NIH HHS R33 HL161775NHLBI NIH HHS R61 HL161775
6 · The paper itself

Abstract

The Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia (CARE-FH) study aims to improve diagnostic evaluation rates for FH at Geisinger, an integrated health delivery system. This clinical trial relies upon implementation science to transition the initial evaluation for FH into primary care, attempting to identify individuals prior to the onset of atherosclerotic cardiovascular disease events. The protocol for the CARE-FH study of this paper is available online. The first phase of the project focuses on trial design, including the development of implementation strategies to deploy evidence-based guidelines. The second phase will study the intervention, rolled out regionally to internal medicine, community medicine, and pediatric care clinicians using a stepped-wedge design, and analyzing data on diagnostic evaluation rates, and implementation, service, and health outcomes.

Indexed as

cholesterol screeningfamilial hypercholesterolemiaimplementation sciencepreventionprimary care

Identifiers

PMID35455722
PMCPMC9024715

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.