ReviewCells2022
Sarcopenia in Children with Solid Organ Tumors: An Instrumental Era.
Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of sarcopenia on sarcoma patients: a systematic review and meta-analysis.La Radiologia medica · 2025Pooled it
- Assessing the reliability of interprofessional raters on peripheral muscle ultrasonography in pediatric oncology: A prospective observational study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Observational
- CT-Based body composition and nutritional status as predictors of early-treatment chemotherapy-related infections and hematologic toxicity in pediatric cancer: a prospective study.European journal of pediatrics · 2026Observational
- Sarcopenia and sarcopenic obesity after chemotherapy in childhood lymphoma.Annals of hematology · 2026Article
- Comparing muscle mass in children with high-risk neuroblastoma using magnetic resonance imaging and bioelectrical impedance analysis.Translational pediatrics · 2026Article
- Prevalence of undernutrition at admission and associated factors among children with cancer admitted to the University Hospital of Tangier: a cross-sectional study.Frontiers in pediatrics · 2026Article
- Computed tomography-derived sarcopenia, enteral nutritional support, and febrile neutropenia burden in children with acute lymphoblastic leukemia: a retrospective cohort study.Frontiers in pediatrics · 2026Article
- Article
- Correlation Between Age and Body Composition Values Using Bioelectrical Impedance Analysis in Young Children.Cureus · 2025Article
- Are Vitamin D Levels Related to Sarcopenia in Children with Inflammatory Bowel Disease?Journal of clinical medicine · 2025Article
- Growth and physical development of children at apparent risk of sarcopenia.Pediatric research · 2025Article
- Quantification of liver iron overload among pediatric patients with magnetic resonance imaging: current state of the art.Polish journal of radiology · 2025Review
- Bioelectrical Impedance Analysis of Body Composition in Male Childhood Brain Tumor Survivors.Diseases (Basel, Switzerland) · 2024Article
- Clinical significance of sarcopenia in children with neuroblastic tumors.Pediatric surgery international · 2024Observational
- Nutritional status, body composition and diet quality in children with cancer.Frontiers in oncology · 2024Review
- Automated temporalis muscle quantification and growth charts for children through adulthood.Nature communications · 2023Article
- The impact of sarcopenia and sarcopenic obesity on survival in children with Ewing sarcoma and osteosarcoma.Pediatric radiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcopenia has recently been studied in both adults and children and was found to be a prognostic marker for adverse outcome in a variety of patient groups. Our research showed that sarcopenia is a relevant marker in predicting outcome in children with solid organ tumors, such as hepatoblastoma and neuroblastoma. This was especially true in very ill, high-risk groups. Children with cancer have a higher likelihood of ongoing loss of skeletal muscle mass due to a mismatch in energy intake and expenditure. Additionally, the effects of cancer therapy, hormonal alterations, chronic inflammation, multi-organ dysfunction, and a hypermetabolic state all contribute to a loss of skeletal muscle mass. Sarcopenia seems to be able to pinpoint this waste to a high degree in a new and objective way, making it an additional tool in predicting and improving outcome in children. This article focuses on the current state of sarcopenia in children with solid organ tumors. It details the pathophysiological mechanisms behind sarcopenia, highlighting the technical features of the available methods for measuring muscle mass, strength, and function, including artificial intelligence (AI)-based techniques. It also reviews the latest research on sarcopenia in children, focusing on children with solid organ tumors.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.