Evidence map›Paper›PMID 35458219›Full record

ArticleNutrients2022

Gut Microbial Signatures of Distinct Trimethylamine N-Oxide Response to Raspberry Consumption.

Maximilien Franck, Juan de Toro-Martín, Thibault V Varin, Véronique Garneau, Geneviève Pilon, Denis Roy, Patrick Couture, Charles Couillard, André Marette, Marie-Claude Vohl

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Maximilien FranckInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, QC G1V 0A6, Canada.
Juan de Toro-MartínInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, QC G1V 0A6, Canada.
Thibault V VarinInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, QC G1V 0A6, Canada.
Véronique GarneauInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, QC G1V 0A6, Canada.
Geneviève PilonInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, QC G1V 0A6, Canada.
Denis RoyInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, QC G1V 0A6, Canada.ORCID 0000-0002-4229-9245
Patrick CoutureInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, QC G1V 0A6, Canada.
Charles CouillardInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, QC G1V 0A6, Canada.ORCID 0000-0002-6281-8663
André MaretteInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, QC G1V 0A6, Canada.ORCID 0000-0003-3950-5973
Marie-Claude VohlInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, QC G1V 0A6, Canada.ORCID 0000-0002-7017-5848
Université Laval · CAInstitut universitaire de cardiologie et de pneumologie de Québec · CA

Funding

CIHR MRT-168045WA Red Raspberry Commission (WRRC) not applicable
6 · The paper itself

Abstract

The aim of this exploratory study was to evaluate the gut microbial signatures of distinct trimethylamine N-oxide (TMAO) responses following raspberry consumption. Investigations were carried out in 24 subjects at risk of developing metabolic syndrome who received 280 g/day of frozen raspberries for 8 weeks. Blood and stool samples were collected at weeks 0 and 8. Inter-individual variability in plasma TMAO levels was analyzed, 7 subjects were excluded due to noninformative signals and 17 subjects were kept for analysis and further stratified according to their TMAO response. Whole-metagenome shotgun sequencing analysis was used to determine the impact of raspberry consumption on gut microbial composition. Before the intervention, the relative abundance of Actinobacteriota was significantly higher in participants whose TMAO levels increased after the intervention (

Indexed as

Gastrointestinal MicrobiomeRubusBacteriaHumansMethylaminesMethylaminestrimethyloxaminegut microbiotametabolic disordersraspberryTMAO

Identifiers

PMID35458219
PMCPMC9027468
OpenAlexW4224229860

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.