Evidence map›Paper›PMID 35463916›Full record

ArticleInternational journal of cardiology. Heart & vasculature2022

Hypovitaminosis D and cardiovascular outcomes: A systematic review and meta-analysis.

Vikash Jaiswal, Angela Ishak, Song Peng Ang, Nishan Babu Pokhrel, Nishat Shama, Kriti Lnu, Jeffy Susan Varghese, Tatyana Storozhenko, Jia Ee Chia, Sidra Naz and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Shift Work and Serum Vitamin D Levels: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  4. [Interpretation of the Expert Consensus Statement on the Role of Vitamin D in Metabolic Health].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Article
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  6. Review
  7. Vitamin D and cardiovascular diseases: A narrative review.Journal of family medicine and primary care · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 8 countries.

Vikash JaiswalAMA School of Medicine, Makati, Philippines.
Angela IshakEuropean University Cyprus, School of Medicine, Nicosia, Cyprus.
Song Peng AngSchool of Medicine, International Medical University, Kuala Lumpur, Malaysia.
Nishan Babu PokhrelTribhuvan University Institute of Medicine, Maharajgunj, Kathmandu, Nepal.
Nishat ShamaBangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital, Dhaka, Bangladesh.
Kriti LnuDepartment of Internal Medicine, UPMC Harrisburg, PA, USA.
Jeffy Susan VargheseDepartment of Cardiology, St. John's Medical College, Bangalore, India.
Tatyana StorozhenkoGovernment Institution "L.T. Malaya Therapy National Institute NAMSU", Kharkiv, Ukraine.
Jia Ee ChiaSchool of Medicine, International Medical University, Kuala Lumpur, Malaysia.
Sidra NazBIDMC, Harvard Medical School, USA.
Prachi SharmaDepartment of Cardiology, King George's Medical University, Lucknow, India.
Akash JaiswalDepartment of Geriatric Medicine, All India Institute of Medical Science, New Delhi, India.
International Medical University · MYAll India Institute of Medical Sciences · INAMA Computer University · PHBangladesh Institute of Research and Rehabilitation for Diabetes Endocrine and Metabolic Disorders · BDEuropean University Cyprus · CYHarvard University · USKing George's Medical University · INL.T. Malaya National Therapy Institute of the National Academy of Medical Sciences of Ukraine · UASt.John's Medical College Hospital · INTribhuvan University Teaching Hospital · NPUPMC Central Pa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The relation between blood vitamin D levels and the risk of cardiovascular outcomes is debatable. To our knowledge this is the first comparative Methods: Online databases including PubMed, Embase and Cochrane Central were queried to compare the cardiovascular outcomes among hypovitaminosis D (HVD) and control group. The outcomes assessed included differences in major adverse cardiovascular events (MACE), mortality, myocardial infarction, and heart failure. Unadjusted odds ratios (OR) were calculated using a random-effect model with a 95% confidence interval (CI) and P less than 0.05 as a statistical significance. Results: A total of 8 studies including 426,039 patients were included in this analysis. HVD group was associated with a higher incidence of MACE (OR 1.92, 95% CI 1.24 to 2.98, p = 0.003), while there was no significant association of HVD and all-cause mortality (OR 1.77, 95% CI 0.75 to 4.17, p = 0.19), risk of myocardial infarction (OR 0.69, 95% CI 0.39 to 1.24, p = 0.22), and heart failure (OR 1.20, 95% CI 0.34 to 4.25, p = 0.78). Conclusions: This

Indexed as

ACM, All Cause MortalityCardiovascular diseaseHF, Heart FailureHVD, Hypovitaminosis DHypovitaminosisMACE, Major adverse cardiovascular eventsMI, Myocardial InfarctionMortalityVitamin D

Identifiers

PMID35463916
PMCPMC9019228
OpenAlexW4223646502

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.