SynthesisFrontiers in physiology2022
Is There a Minimum Effective Dose for Vascular Occlusion During Blood Flow Restriction Training?
Synthesis in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Blood Flow Restriction (BFR) on Rehabilitation Protocols Following Anterior Cruciate Ligament Reconstruction (ACLR) With Quadricep Autograft
Effects of Blood Flow Restriction Combined With Electrostimulation After Knee Arthroplasty: Randomized Controlled Trial
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Blood flow restriction combined with resistance training on muscle strength and thickness improvement in young adults: a systematic review, meta-analysis, and meta-regression.Frontiers in physiology · 2024Pooled it
- Arterio-venous metabolite and electrolyte responses to low-load training with and without blood flow restriction versus high-load training to failure.European journal of applied physiology · 2026Trial
- Neuromuscular adaptations to caffeine supplementation in low-load resistance training with blood flow restriction.Journal of the International Society of Sports Nutrition · 2025Trial
- The Reliability and Validity of Manual Palpation to Assess Lower Limb Arterial Occlusion Pressure in Older Adults, for Application in Blood Flow Restriction Exercise.European journal of sport science · 2026Article
- Acute Effects of Low-Intensity Blood-Flow-Restricted Walking on Pain Sensitivity, Joint Range of Motion, and Myofascial Stiffness in Healthy Adults.Journal of clinical medicine · 2026Article
- Pressure point: blood flow restriction exercise and the pain paradox in musculoskeletal injury and persistent pain populations-a narrative review.Frontiers in pain research (Lausanne, Switzerland) · 2026Review
- Pressure prescription in blood flow restriction training: evaluating the role of arterial occlusion pressure.Frontiers in sports and active living · 2026Review
- Calcific Patellar Tendinopathy. A Case Report Integrating Diagnostic Ultrasound Throughout a Multi-Modal Treatment Approach.International journal of sports physical therapy · 2026Article
- Methodological Approach to Predicting Lower Limb Blood Flow Restriction Pressure Using Anthropometry and Hemodynamics.Life (Basel, Switzerland) · 2025Article
- The effect of blood flow restriction combined with neuromuscular electrical stimulation on knee joint function: A systematic review and meta-analysis.Journal of orthopaedics · 2025Review
- Qualitative Evaluation of Patient Experiences with Low-Load Blood Flow Restriction and Heavy-Load Resistance Training Post-ACL Reconstruction.International journal of sports physical therapy · 2025Article
- Acute effects of blood flow restriction training at various arterial occlusion pressures on muscle activation, blood lactate responses, and RPE in healthy adult males.Frontiers in physiology · 2025Article
- Comparative analysis of high-intensity resistance training and blood flow restriction training on enhancing upper limb muscle strength and mass.Frontiers in physiology · 2025Article
- Clinic and Home-Based Exercise with Blood Flow Restriction Resolves Thigh Muscle Atrophy after Anterior Cruciate Ligament Reconstruction with the Bone-Patellar Tendon-Bone Autograft: A Case Report.Healthcare (Basel, Switzerland) · 2023Article
- Acute effects of low load blood flow restricted and non restricted exercise on muscle excitation, neuromuscular efficiency, and average torque.Journal of musculoskeletal & neuronal interactions · 2023Article
- Commentary: Is there a minimum effective dose for vascular occlusion during blood flow restriction training?Frontiers in physiology · 2023Article
- Neuromuscular Responses to Failure vs Non-Failure During Blood Flow Restriction Training in Untrained Females.International journal of exercise science · 2023Article
- Comparing low volume of blood flow restricted to high-intensity resistance training of the finger flexors to maintain climbing-specific strength and endurance: a crossover study.Frontiers in sports and active living · 2023Article
- Blood flow restriction added to usual care exercise in patients with early weight bearing restrictions after cartilage or meniscus repair in the knee joint: a feasibility study.Journal of experimental orthopaedics · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Blood flow restriction (BFR) training at lower exercise intensities has a range of applications, allowing subjects to achieve strength and hypertrophy gains matching those training at high intensity. However, there is no clear consensus on the percentage of limb occlusion pressure [%LOP, expressed as a % of the pressure required to occlude systolic blood pressure (SBP)] and percentage of one repetition max weight (%1RM) required to achieve these results. This review aims to explore what the optimal and minimal combination of LOP and 1RM is for significant results using BFR. Method: A literature search using PubMed, Scopus, Wiley Online, Springer Link, and relevant citations from review papers was performed, and articles assessed for suitability. Original studies using BFR with a resistance training exercise intervention, who chose a set %LOP and %1RM and compared to a non-BFR control were included in this review. Result: Twenty-one studies met the inclusion criteria. %LOP ranged from 40 to 150%. %1RM used ranged from 15 to 80%. Training at 1RM ≤20%, or ≥ 80% did not produce significant strength results compared to controls. Applying %LOP of ≤50% and ≥ 80% did not produce significant strength improvement compared to controls. This may be due to a mechanism mediated by lactate accumulation, which is facilitated by increased training volume and a moderate exercise intensity. Conclusion: Training at a minimum of 30 %1RM with BFR is required for strength gains matching non-BFR high intensity training. Moderate intensity training (40-60%1RM) with BFR may produce results exceeding non-BFR high intensity however the literature is sparse. A %LOP of 50-80% is optimal for BFR training.
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.