Evidence map›Paper›PMID 35464096›Full record

ArticleFrontiers in physiology2022

Dietary Inclusion of Seabuckthorn (

Ming Li, Xuyang Zhao, Jiayuan Xie, Xinyu Tong, Junwei Shan, Mijuan Shi, Guangxin Wang, Weidong Ye, Yuhang Liu, Bruno Hamish Unger and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Heliyon · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Ming LiInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Xuyang ZhaoInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Jiayuan XieInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Xinyu TongHubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan, China.
Junwei ShanInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Mijuan ShiInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Guangxin WangInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Weidong YeInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Yuhang LiuInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Bruno Hamish UngerInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Yingyin ChengInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Wanting ZhangInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Nan WuInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Xiao-Qin XiaInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Institute of Hydrobiology · CNChinese Academy of Sciences · CNDalian Ocean University · CNUniversity of Chinese Academy of Sciences · CNHuazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To help prevent foodborne enteritis in aquaculture, several feed additives, such as herbal medicine, have been added to fish diets. Predictions of effective herb medicines for treating fish foodborne enteritis from key regulated DEGs (differentially expressed genes) in transcriptomic data can aid in the development of feed additives using the Traditional Chinese Medicine Integrated Database. Seabuckthorn has been assessed as a promising candidate for treating grass carp soybean-induced enteritis (SBMIE). In the present study, the SBMIE zebrafish model was used to assess seabuckthorn's therapeutic or preventative effects. The results showed that intestinal and hepatic inflammation was reduced when seabuckthorn was added, either pathologically (improved intestinal villi morphology, less oil-drops) or growth-related (body fat deposition). Moreover, seabuckthorn may block the intestinal p53 signaling pathway, while activating the PPAR signaling pathway and fatty acid metabolism in the liver. 16S rRNA gene sequencing results also indicated a significant increase in OTU numbers and skewed overlapping with the fish meal group following the addition of seabuckthorn. Additionally, there were signs of altered gut microbiota taxa composition, particularly for reduced TM7,

Indexed as

anti-inflammationfatty acid metabolismherb therapyimmune crosstalkintestinal microbiota

Identifiers

PMID35464096
PMCPMC9019508
OpenAlexW4225553690

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.