Evidence map›Paper›PMID 35465260›Full record

ArticleInternational medical case reports journal2022

Severe Carbamazepine Toxicity Treated with Continuous Venovenous Hemofiltration at Palestine Medical Complex: Two Case Reports.

Mowaffaq A Nasif, Hiba H Falana, Heba K H Hamed, Qusai G H Yousef, Mohammad A Jaradat

Open access · goldAbstract readCase Reports
In one paragraph

Article in International medical case reports journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mowaffaq A NasifIntensive Care Unit, Palestine Medical Complex, Ramallah, Palestine.
Hiba H FalanaDepartment of Pharmacy, Birzeit University, Ramallah, Palestine.ORCID 0000-0002-3462-8141
Heba K H HamedIntensive Care Unit, Palestine Medical Complex, Ramallah, Palestine.
Qusai G H YousefInternal Medicine Department, Al-Quds University, Jerusalem, Palestine.
Mohammad A JaradatIntensive Care Unit, Palestine Medical Complex, Ramallah, Palestine.
Al-Quds University · PSBirzeit University · PS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbamazepine intoxication is not uncommon and accounts for many cases of poisoning among anticonvulsive medications users. Since there is no specific antidote for carbamazepine overdose, management is limited to gastric decontamination and supportive therapy. With its high protein binding, the role of extracorporeal elimination in carbamazepine intoxication is still questionable. Here two cases of severe carbamazepine intoxication are presented; the cases were brought to the emergency department after the ingestion of 12,000 mg of controlled release carbamazepine for the first case, and unknown amounts of the same drug for the second case. Both cases were presented with altered mental status, convulsion, and high serum carbamazepine levels of more than 20 mcg/mL. They were intubated and treated with continuous venovenous hemofiltration, after which carbamazepine levels declined significantly along with subsequent clinical improvement and complete neurological recovery. Both cases were discharged home for further psychiatric care.

Indexed as

carbamazepinecontinuous renal replacement therapypoisoning

Identifiers

PMID35465260
PMCPMC9022740
OpenAlexW4224076320

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.