Evidence map›Paper›PMID 35471092›Full record

ArticleMicrobiology spectrum2022

A Velvet Transcription Factor Specifically Activates Mating through a Novel Mating-Responsive Protein in the Human Fungal Pathogen Cryptococcus deneoformans.

Huimin Liu, Xiaoxia Yao, Weixin Ke, Hao Ding, Guang-Jun He, Shuang Ma, Yan Peng, Xinping Xu, Guojian Liao, Xiuyun Tian and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Huimin Liu *School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China (USTC), Hefei, China.
Xiaoxia Yao *State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Weixin KeState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Hao DingState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Guang-Jun HeState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Shuang MaState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Yan PengCollege of Pharmaceutical Sciences, Medical Research Institute, Southwest University, Chongqing, China.
Xinping XuJiangxi Institute of Respiratory Disease, The First Affiliated Hospital of Nanchang University, Jiangxi, China.
Guojian LiaoCollege of Pharmaceutical Sciences, Medical Research Institute, Southwest University, Chongqing, China.
Xiuyun TianState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Linqi WangSchool of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China (USTC), Hefei, China.ORCID 0000-0002-5243-341X
Chinese Academy of Sciences · CNSouthwest University · CNUniversity of Science and Technology of China · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sexual reproduction facilitates infection by the production of both a lineage advantage and infectious sexual spores in the ubiquitous human fungal pathogen Cryptococcus deneoformans. However, the regulatory determinants specific for initiating mating remain poorly understood. Here, we identified a velvet family regulator, Cva1, that strongly promotes sexual reproduction in C. deneoformans. This regulation was determined to be specific, based on a comprehensive phenotypic analysis of

Indexed as

Cryptococcus neoformansFungal ProteinsGenes, Mating Type, FungalTranscription FactorsMeiosisFungal ProteinsTranscription Factorscell-cell fusionCryptococcusmatingsexual reproductionvelvet protein family

Identifiers

PMID35471092
PMCPMC9241590
OpenAlexW4224859693

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.