Trial reportAnnals of medicine2022
Relative fat mass assessment estimates changes in adiposity among female older adults with obesity after a 12-month exercise and diet intervention.
Trial report in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00955903 (Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults), which is not on this map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults
Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Association of relative fat mass with the incidence of type 2 diabetes: over a decade follow-up from the TLGS.International journal of obesity (2005) · 2025Article
- The Significance of Relative Fat Mass in Chronic Obstructive Pulmonary Disease Prevalence and Severity: Evidences From Two Cohorts.International journal of chronic obstructive pulmonary disease · 2025Article
- Negative correlation between relative fat mass and bone mineral density: NHANES 2011-2018.Frontiers in public health · 2025Article
- Prevalence and risk factors of obesity among undergraduate student population in Ghana: an evaluation study of body composition indices.BMC public health · 2024Article
- Antiaging Strategies and Remedies: A Landscape of Research Progress and Promise.ACS chemical neuroscience · 2024Review
- Body Composition Evaluation and Clinical Markers of Cardiometabolic Risk in Patients with Phenylketonuria.Nutrients · 2023Review
- Relative fat mass and prediction of incident atrial fibrillation, heart failure and coronary artery disease in the general population.International journal of obesity (2005) · 2023Article
- Article
- Iron Levels and Markers of Inflammation in a Population of Adults with Severe Obesity, a Cross-Sectional Study.Nutrients · 2023Article
- Association between BMI, RFM and mortality and potential mediators: Prospective findings from the Moli-sani study.International journal of obesity (2005) · 2023Article
- Performance of Body Adiposity Index and Relative Fat Mass in Predicting Bioelectric Impedance Analysis-Derived Body Fat Percentage: A Cross-Sectional Study among Patients with Type 2 Diabetes in the Ho Municipality, Ghana.BioMed research international · 2023Article
- Changes in Novel Anthropometric Indices of Abdominal Obesity during Weight Loss with Selected Obesity-Associated Single-Nucleotide Polymorphisms: A Small One-Year Pilot Study.International journal of environmental research and public health · 2022Article
- Development and Validation of Waist Girth-Based Equations to Evaluate Body Composition in Colombian Adults: Rationale and STROBE-Nut-Based Protocol of the F20 Project.International journal of environmental research and public health · 2022Observational
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
BACKGROUND/OBJECTIVES/
introductionIt is imperative to accurately estimate whole body fat percentage (%fat) to understand the deleterious nature of excess adiposity on cardiometabolic disease risk. Cost and accessibility often preclude the use of advanced imaging methods like dual-energy X-ray absorptiometry (DXA) and magnetic resonance imaging (MRI). Relative fat mass (RFM) is an emerging estimator of whole body %fat based on waist circumference, height, and biological sex. The purpose of this ancillary study was to examine the relationship between RFM and gold-standard measures of adiposity among community-dwelling older adults with obesity and to evaluate if changes in RFM reflect changes in %fat following a 12-month lifestyle intervention (clinicaltrials.gov #NCT00955903). PATIENTS/MATERIALS AND
methodsParticipants (
resultsRFM was significantly positively correlated with DXA whole body %fat and DXA trunk %fat at baseline. Equivalence testing revealed that RFM was considered equivalent to DXA whole body %fat for females only. Additionally, from baseline to 12 months, a significant reduction in RFM was observed among female participants in the exercise + energy restriction group only. Changes in RFM were significantly correlated with changes in DXA whole body %fat, DXA trunk fat, and total abdominal fat tissue determined by MRI.
conclusionResults support the use of RFM as an estimate of whole body %fat where advanced imaging techniques are not feasible. Furthermore, results suggest that this index is sensitive to changes in fat mass over 12 months in female older adults with obesity. KEY MESSAGESRelative fat mass (RFM), an emerging estimator of whole body %fat based on waist circumference, height, and biological sex, was intentionally developed to be a simple estimate of adiposity that overcomes limitations of measures like body mass index.In the current study, results from correlations and agreement analyses support the use of RFM to estimate whole-body fat percentage in a community-dwelling older adult population with obesity when advanced methods, namely dual-energy X-ray absorptiometry, are not feasible.Significant reductions in RFM were also observed over a 12-month period that was significantly correlated with changes in whole body fat percentage; thus, supporting the sensitivity of RFM to lifestyle changes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.