Evidence map›Paper›PMID 35473672›Full record

ArticleBMC cardiovascular disorders2022

Reconsidering treatment guidelines for acute myocardial infarction during the COVID-19 pandemic.

Jing Gao, Peng-Ju Lu, Chang-Ping Li, Hui Wang, Ji-Xiang Wang, Nan Zhang, Xiao-Wei Li, Hai-Wang Zhao, Jing Dou, Miao-Na Bai and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Jing Gao *Chest Hospital, Tianjin University, No. 92 Weijin Road Nankai District, Tianjin, 300072, People's Republic of China.
Peng-Ju Lu *Department of Cardiology, Tianjin Chest Hospital, No. 261 Tai er zhuang Road, Jinnan District, Tianjin, 300222, People's Republic of China.
Chang-Ping LiTianjin Medical University, No.22 Qi xiang tai Road, Heping District, Tianjin, 300070, People's Republic of China.
Hui WangTianjin Medical University, No.22 Qi xiang tai Road, Heping District, Tianjin, 300070, People's Republic of China.
Ji-Xiang WangDepartment of Cardiology, Tianjin Chest Hospital, No. 261 Tai er zhuang Road, Jinnan District, Tianjin, 300222, People's Republic of China.
Nan ZhangDepartment of Cardiology, Tianjin Chest Hospital, No. 261 Tai er zhuang Road, Jinnan District, Tianjin, 300222, People's Republic of China.
Xiao-Wei LiDepartment of Cardiology, Tianjin Chest Hospital, No. 261 Tai er zhuang Road, Jinnan District, Tianjin, 300222, People's Republic of China.
Hai-Wang ZhaoDepartment of Cardiology, Tianjin Chest Hospital, No. 261 Tai er zhuang Road, Jinnan District, Tianjin, 300222, People's Republic of China.
Jing DouDepartment of Cardiology, Tianjin Chest Hospital, No. 261 Tai er zhuang Road, Jinnan District, Tianjin, 300222, People's Republic of China.
Miao-Na BaiDepartment of Cardiology, Tianjin Chest Hospital, No. 261 Tai er zhuang Road, Jinnan District, Tianjin, 300222, People's Republic of China.
Yu-Tian ShiDepartment of Cardiology, Tianjin Chest Hospital, No. 261 Tai er zhuang Road, Jinnan District, Tianjin, 300222, People's Republic of China.
Jia ZhaoDepartment of Cardiology, Tianjin Chest Hospital, No. 261 Tai er zhuang Road, Jinnan District, Tianjin, 300222, People's Republic of China.
Chun ZanDepartment of Cardiology, Tianjin Chest Hospital, No. 261 Tai er zhuang Road, Jinnan District, Tianjin, 300222, People's Republic of China.
Yin LiuDepartment of Cardiology, Tianjin Chest Hospital, No. 261 Tai er zhuang Road, Jinnan District, Tianjin, 300222, People's Republic of China. liuyin2088@163.com.
Tianjin Chest Hospital · CNTianjin Medical University · CNTianjin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 affects healthcare resource allocation, which could lead to treatment delay and poor outcomes in patients with acute myocardial infarction (AMI). We assessed the impact of the COVID-19 pandemic on AMI outcomes.

methodsWe compared outcomes of patients admitted for acute ST-elevation MI (STEMI) and non-STEMI (NSTEMI) during a non-COVID-19 pandemic period (January-February 2019; Group 1, n = 254) and a COVID-19 pandemic period (January-February 2020; Group 2, n = 124).

resultsFor STEMI patients, the median of first medical contact (FMC) time, door-to-balloon time, and total myocardial ischemia time were significantly longer in Group 2 patients (all p < 0.05). Primary percutaneous intervention was performed significantly more often in Group 1 patients than in Group 2 patients, whereas thrombolytic therapy was used significantly more often in Group 2 patients than in Group 1 patients (all p < 0.05). However, the rates of and all-cause 30-day mortality and major adverse cardiac event (MACE) were not significantly different in the two periods (all p > 0.05). For NSTEMI patients, Group 2 patients had a higher rate of conservative therapy, a lower rate of reperfusion therapy, and longer FMC times (all p < 0.05). All-cause 30-day mortality and MACE were only higher in NSTEMI patients during the COVID-19 pandemic period (p < 0.001).

conclusionsCOVID-19 pandemic causes treatment delay in AMI patients and potentially leads to poor clinical outcome in NSTEMI patients. Thrombolytic therapy should be initiated without delay for STEMI when coronary intervention is not readily available; for NSTEMI patients, outcomes of invasive reperfusion were better than medical treatment.

Indexed as

COVID-19Myocardial InfarctionNon-ST Elevated Myocardial InfarctionST Elevation Myocardial InfarctionHumansPandemicsTime FactorsTreatment OutcomeAcute myocardial infarctionCoronavirus disease-2019First medical contact timeMajor adverse cardiac event

Identifiers

PMID35473672
PMCPMC9040353
OpenAlexW4224998902

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.