ArticleJournal of diabetes investigation2022
Adherence to healthy lifestyle behaviors as a preventable risk factor for severe hypoglycemia in people with type 2 diabetes: A longitudinal nationwide cohort study.
Article in Journal of diabetes investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- Sex differences in glycemic outcomes: a systematic review and meta-analysis of diabetes treatments.BMJ open diabetes research & care · 2026Pooled it
- Risk Factors of Diabetic Bladder Dysfunction in Patients with Type 2 Diabetes Mellitus: A Case-Control Study in Shenzhen, China.International urogynecology journal · 2026Article
- The association of incident abdominal obesity with diet and unfavorable lifestyle factors in Korean adults: A prospective cohort study.Medicine · 2026Observational
- Machine learning-based online prediction of nocturnal hypoglycemia in elderly patients with type 2 diabetes.Frontiers in endocrinology · 2025Article
- Effect of smoking on the risk of gastrointestinal cancer after cholecystectomy: A national population-based cohort study.World journal of gastrointestinal surgery · 2024Article
- Diabetes Mellitus in the Elderly Adults in Korea: Based on Data from the Korea National Health and Nutrition Examination Survey 2019 to 2020.Diabetes & metabolism journal · 2023Article
- Socioecological influencers of health-promoting lifestyles in Chinese: a preliminary survey using convenient samples.Frontiers in public health · 2023Article
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Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
Abstract
AIMS/
introductionWe investigated the associations between a combination of lifestyle factors and changes to these factors and the subsequent risk of severe hypoglycemia (SH) in type 2 diabetes patients. MATERIALS AND
methodsIndividuals with adult type 2 diabetes who underwent consecutive 2-year interval health screening programs from 2009 to 2012 from the Korean National Health Insurance Service database were included and followed up until 2018. Information on history of smoking status, alcohol consumption and physical activity, as well as changes to these factors, was obtained. The primary outcome was incident SH.
resultsOf the 1,490,233 type 2 diabetes patients, 30,539 (2.1%) patients developed SH. Current smokers and heavy drinkers had increased risk of SH, compared with non-smokers and non-drinkers, respectively (hazard ratio 1.28, 95% confidence interval 1.23-1.34; hazard ratio 1.22, 95% confidence interval 1.15-1.30). However, regular physical activity was associated with reduced SH risk (hazard ratio 0.79, 95% confidence interval 0.77-0.82). A combination of unhealthy lifestyle habits was associated with increased SH risk in a dose-dependent fashion (P for trend <0.001). Compared with participants without changes in their unhealthy lifestyles, participants who improved lifestyles had decreased risk of SH.
conclusionsGreater adherence to healthy lifestyle factors and any improvement in unhealthy lifestyle habits were associated with a substantially lower risk of SH in individuals with type 2 diabetes.
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